Evidence map›Paper›PMID 31469451›Full record

ArticleAlcoholism, clinical and experimental research2019

Temporal Dynamics of Transdermal Alcohol Concentration Measured via New-Generation Wrist-Worn Biosensor.

Catharine E Fairbairn, Dahyeon Kang

Registry-linked trialOpen access · greenAbstract readEvaluation Study
In one paragraph

Article in Alcoholism, clinical and experimental research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05692830 (Towards a Wearable Alcohol Biosensor), which is not on this map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
6.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05692830 recruitingnot on this mapstarted 2022, after this paper: background citation

Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms

TypeobservationalSponsorUniversity of Illinois at Urbana-ChampaignRan2022 to 2027Enrolled240ConditionsAlcohol Drinking, Alcohol IntoxicationArmsAlcohol
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Pooled it
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  9. Drinking intention-behavior links vary by affect among heavy-drinking young adults: An ecological momentary assessment and transdermal sensor study.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
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  16. College Students' Day-to-Day Maladaptive Drinking Responses to Stress Severity and Stressor-Related Guilt and Anger.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2024
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  17. Accuracy of transdermal alcohol monitoring devices in a laboratory setting.Alcohol and alcoholism (Oxford, Oxfordshire) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Catharine E FairbairnDepartment of Psychology, University of Illinois-Urbana-Champaign, Champaign, Illinois.ORCID 0000-0002-2694-5585
Dahyeon KangDepartment of Psychology, University of Illinois-Urbana-Champaign, Champaign, Illinois.ORCID 0000-0003-4248-2098
University of Illinois Urbana-Champaign · US

Funding

Examining the Impact of Stress on the Emotionally Reinforcing Properties of Alcohol in Heavy Social Drinkers: A Multimodal Investigation Integrating Laboratory and Ambulatory MethodsR01AA025969 · NIAAA · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Catharine Fairbairn · 2017 to 2026
$3.5M
NIAAA NIH HHS R01 AA025969
6 · The paper itself

Abstract

backgroundThe development of a transdermal alcohol biosensor could represent a tremendous advance toward curbing problematic drinking. But several factors limit the usefulness of extant transdermal technology, including relatively lengthy delays between blood alcohol concentration (BAC) and transdermal alcohol concentration (TAC), as well as the large/bulky designs of currently available transdermal sensors (e.g., ankle monitors). The current research examined the lag time between BAC and TAC using a prototype of BACtrack Skyn-a new-generation wrist-worn transdermal sensor featuring a compact design and smartphone integration.

methodsParticipants (N = 30) received either a dose of alcohol (target BAC 0.08%) or a nonalcoholic beverage in the laboratory while wearing both the AMS SCRAM ankle monitor and a Skyn prototype. Participants were monitored in the laboratory until breath alcohol concentration (BrAC) dropped below 0.025%.

resultsDevice failure rates for Skyn prototypes were relatively high (18 to 38%) compared with nonprototype SCRAM devices (2%). Among participants with usable data, both Skyn- and SCRAM-measured TAC showed strong correlations with BrAC, and both Skyn and SCRAM devices detected alcohol within 30 minutes of first alcohol administration. Skyn-measured TAC peaked over 1 hour earlier than SCRAM-measured TAC (54 versus 120 minutes after peak BrAC, respectively), and time-series models suggested that, on average across all measured portions of the BrAC curve, Skyn TAC lagged behind BrAC by 24 minutes, whereas SCRAM TAC lagged behind BrAC by 69 minutes-all differences statistically significant at p < 0.001.

conclusionsResults provide preliminary evidence for the validity of a new-generation wrist-worn transdermal sensor under controlled laboratory conditions and further suggest favorable properties of this sensor as they pertain to the latency of transdermal alcohol detection. The prototype version of Skyn employed here displayed a higher failure rate compared with SCRAM, and, in future, more reliable and robust Skyn prototypes will be required suitable to field testing across diverse environmental conditions.

Indexed as

Biosensing TechniquesAdultAlcohol DrinkingAnkleBlood Alcohol ContentBreath TestsCentral Nervous System DepressantsEquipment DesignEquipment FailureEthanolFemaleHumansMaleMonitoring, PhysiologicSkinSmartphoneBlood Alcohol ContentCentral Nervous System DepressantsEthanolAlcoholBiosensorBlood Alcohol ConcentrationMeasurementTransdermal

Identifiers

PMID31469451
PMCPMC6779481
OpenAlexW2970600748

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.