Evidence map›Paper›PMID 31469438›Full record

ReviewTransfusion2020

The pipeline of antiviral T-cell therapy: what's in the clinic and undergoing development.

Alyssa Fatic, Nan Zhang, Michael D Keller, Patrick J Hanley

Abstract readReview
In one paragraph

Review in Transfusion, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. BK viral infection: A review of management and treatment.World journal of transplantation · 2023
    Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alyssa FaticCenter for Cancer and Immunology Research, Children's National Medical Center, Washington, District of Columbia.ORCID 0000-0002-7613-5214
Nan ZhangCenter for Cancer and Immunology Research, Children's National Medical Center, Washington, District of Columbia.
Michael D KellerCenter for Cancer and Immunology Research, Children's National Medical Center, Washington, District of Columbia.
Patrick J HanleyCenter for Cancer and Immunology Research, Children's National Medical Center, Washington, District of Columbia.

Funding

Adoptive Immunotherapy for the Treatment of Viral Infections in Primary Immunodeficiency DisordersK23HL136783 · NHLBI · CHILDREN'S RESEARCH INSTITUTE · PI KELLER, MICHAEL DANIEL · 2017 to 2019
$614k
NHLBI NIH HHS K23 HL136783
6 · The paper itself

Abstract

Virus-specific T cells allow targeting of multiple pathogens in patients after hematopoietic stem cell transplantation and have demonstrated potential efficacy for cytomegalovirus, Epstein-Barr Virus, and adenovirus. Novel targets may include BK virus, JC virus, varicella zoster virus, human herpesvirus 6, Aspergillus, human parainfluenza virus-3, herpes simplex virus Type I, Zika virus, and mycobacteria. Generation of patient-specific products and third-party products may expand feasibility of therapy.

Indexed as

Adoptive TransferT-LymphocytesVirus DiseasesHumans

Identifiers

PMID31469438
PMCPMC9359816

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.