Evidence map›Paper›PMID 31469354›Full record

ReviewMultiple sclerosis (Houndmills, Basingstoke, England)2019

Beyond rehabilitation: A prevention model of reserve and brain maintenance in multiple sclerosis.

Rachel Brandstadter, Ilana Katz Sand, James F Sumowski

Open access · bronzeAbstract readReview
In one paragraph

Review in Multiple sclerosis (Houndmills, Basingstoke, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. To halt disease progression rehabilitation in MS should start early: No.Multiple sclerosis (Houndmills, Basingstoke, England) · 2024
    Article
  10. To halt disease progression rehabilitation in MS should start early: Yes.Multiple sclerosis (Houndmills, Basingstoke, England) · 2024
    Article
  11. Article
  12. Brain and cognitive reserve mitigate balance dysfunction in multiple sclerosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Article
  13. Article
  14. Mediterranean diet is linked to less objective disability in multiple sclerosis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2023
    Article
  15. Review
  16. Dietary factors and MRI metrics in early Multiple Sclerosis.Multiple sclerosis and related disorders · 2021
    Article
  17. Article
  18. Article
  19. Mobile Brain/Body Imaging of cognitive-motor impairment in multiple sclerosis: Deriving EEG-based neuro-markers during a dual-task walking study.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rachel BrandstadterDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA/Corinne Goldsmith Dickinson Center for MS, Mount Sinai Hospital, New York, NY, USA.
Ilana Katz SandDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA/Corinne Goldsmith Dickinson Center for MS, Mount Sinai Hospital, New York, NY, USA.
James F SumowskiDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA/Corinne Goldsmith Dickinson Center for MS, Mount Sinai Hospital, New York, NY, USA.ORCID 0000-0001-6111-4907
Mount Sinai Hospital · US

Funding

Reserve against Disability in Early Multiple Sclerosis (RADIEMS) Longitudinal Cohort StudyR01HD082176 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SUMOWSKI, JAMES FRANCIS · 2016 to 2025
$6.6M
NICHD NIH HHS R01 HD082176
6 · The paper itself

Abstract

Persons with multiple sclerosis (MS) experience cognitive and physical decline despite more effective disease-modifying therapies (DMTs), and symptomatic treatments currently have limited efficacy. The best treatment of MS disability may, therefore, be prevention of decline. Here, we present a working model of

Indexed as

Disease ProgressionBrainCognitive ReserveHumansMultiple SclerosisProtective FactorsRisk Factorscognitive reservecomorbidityMultiple sclerosisprotective factorsrisk factors

Identifiers

PMID31469354
PMCPMC6719722
OpenAlexW2970431539

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.