Evidence map›Paper›PMID 31469343›Full record

ArticleRNA biology2019

Retroviral-like determinants and functions required for dimerization of Ty1 retrotransposon RNA.

Julita Gumna, Katarzyna J Purzycka, Hyo Won Ahn, David J Garfinkel, Katarzyna Pachulska-Wieczorek

Open access · hybridAbstract read
In one paragraph

Article in RNA biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. GAG Protein ofPlants (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Article
  4. An interchangeable prion-like domain is required for Ty1 retrotransposition.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. RNA Binding Properties of the Ty1 LTR-Retrotransposon Gag Protein.International journal of molecular sciences · 2021
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Julita GumnaDepartment of Structure and Function of Retrotransposons, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.ORCID 0000-0002-1045-2823
Katarzyna J PurzyckaDepartment of Structure and Function of Retrotransposons, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.ORCID 0000-0002-0271-9161
Hyo Won AhnDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, USA.
David J GarfinkelDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, USA.ORCID 0000-0001-6234-2426
Katarzyna Pachulska-WieczorekDepartment of Structure and Function of Retrotransposons, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.ORCID 0000-0002-5723-6204
Institute of Bioorganic Chemistry, Polish Academy of Sciences · PLUniversity of Georgia · US

Funding

Effectors of retrotransposon movementR01GM124216 · NIGMS · UNIVERSITY OF GEORGIA · PI GARFINKEL, DAVID J. · 2018 to 2021
$1.9M
Antisense RNAs control retrotransposon copy numberR01GM095622 · NIGMS · UNIVERSITY OF GEORGIA · PI GARFINKEL, DAVID J. · 2011 to 2014
$1.1M
NIGMS NIH HHS R01 GM095622NIGMS NIH HHS R01 GM124216
6 · The paper itself

Abstract

During replication of long terminal repeat (LTR)-retrotransposons, their proteins and genome (g) RNA assemble into virus-like particles (VLPs) that are not infectious but functionally related to retroviral virions. Both virions and VLPs contain gRNA in a dimeric form, but contrary to retroviruses, little is known about how gRNA dimerization and packaging occurs in LTR-retrotransposons. The LTR-retrotransposon Ty1 from

Indexed as

Retroelements5' Untranslated RegionsBase PairingBase SequenceDimerizationModels, MolecularMutationNucleic Acid ConformationRetroviridaeRNA, TransferRNA, ViralSaccharomyces cerevisiaeVirionVirus Replication5' Untranslated RegionsRetroelementsRNA, TransferRNA, ViralGagLTR-retrotransposonsRNA dimerizationRNA structureTy1

Identifiers

PMID31469343
PMCPMC6844567
OpenAlexW2970286176

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.