Observational studyThe British journal of radiology2019
Bone islands incidentally detected on computed tomography: frequency of enostosis and differentiation from untreated osteoblastic metastases based on CT attenuation value.
Observational study in The British journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 31 citations in OpenAlex.
- Diagnostic performance of dual-layer spectral CT Radiomics and deep learning for differentiating osteoblastic bone metastases from bone islands.European journal of radiology open · 2025Article
- Unveiling Primary Bone Tumors of the Spine: A Review of Essential Imaging Clues.Diagnostics (Basel, Switzerland) · 2025Review
- [Basic principles of the diagnostics and treatment of malignant bone tumors in old age].Orthopadie (Heidelberg, Germany) · 2025Review
- Conventional radiography for the assessment of focal bone lesions of the appendicular skeleton: fundamental concepts in the modern imaging era.Skeletal radiology · 2025Review
- A spectral CT-derived metrics-based radiomics model in differentiatingFrontiers in oncology · 2025Article
- Osteopoikilosis in a patient with familial adenopolyposis : A case report.Radiology case reports · 2024Article
- Imaging of Sacroiliac Pain: The Current State-of-the-Art.Journal of personalized medicine · 2024Review
- Incidental Findings in Lung Cancer Screening.Cancers · 2024Review
- Article
- [Bone-RADS: Diagnostic algorithm for management of incidental solitary bone lesions].Radiologie (Heidelberg, Germany) · 2024Article
- Spectral CT assists differentiation of osteoblastic bone metastasis from bone island in newly diagnosed cancer patients.European radiology · 2024Article
- Deep learning-based diagnosis of osteoblastic bone metastases and bone islands in computed tomograph images: a multicenter diagnostic study.European radiology · 2023Article
- Application of Machine Learning for Differentiating Bone Malignancy on Imaging: A Systematic Review.Cancers · 2023Review
- Benign incidental do-not-touch bone lesions.The British journal of radiology · 2023Review
- Society of Skeletal Radiology- white paper. Guidelines for the diagnostic management of incidental solitary bone lesions on CT and MRI in adults: bone reporting and data system (Bone-RADS).Skeletal radiology · 2022Review
- Observational
- Dual-Energy Computed Tomography For Differentiation Between Osteoblastic Metastases and Bone Islands.Frontiers in oncology · 2022Article
- Imaging Review of Pediatric Benign Osteocytic Tumors and Latest Updates on Management.Journal of clinical medicine · 2021Review
- Article
- Atypical Enostoses-Series of Ten Cases and Literature Review.Medicina (Kaunas, Lithuania) · 2020Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe frequency of enostosis incidentally found on CT and CT attenuation value to distinguish them from untreated osteoblastic metastases (UOM).
methodsEnostosis group: 46 polytrauma patients underwent thoracoabdominal CT. Inclusion criteria: age range 14-35 years. Exclusion criteria: cancer, previous fractures. UOM group: 20 patients with radiological diagnosis of UOM. Analyzed data: number, size, location and density of enostoses and metastases. The density was measured with the broadest possible region of interest at the center of the lesion by two radiologists independently. Receiver operatingcharacteristic analysis to determine the sensitivity and specificity, area under the curve 95% confidence intervals and cutoff values of CT density to differentiate metastases from enostoses.
resultsPatients were 28 ± 7 years old (72% males). 41 (89%) patients had 124 enostoses (2-15 mm) with an average density of 1007 ± 122 Hounsfiled unit (HU, observer1) and 1052 ± 107 (observer2). The most common sites of occurrence were the proximal femur (34%), the pelvis (22%), the acetabulum (20%), the proximal humerus (11%), the vertebrae (11%) and the rib (2%). 13 patients had 1 bone island, 8 patients had 2, 9 cases had 3 and 11 cases had more than 3 enostoses. Overall, 114 UOM were evaluated, their average density was 728 ± 163 HU (observer1) and 712 ± 178 HU (observer2). The area under the curve value of mean density to distinguish enostoses from UOM was 0,982. Using a cut-off of 881 HU for mean density, sensitivity was 98% and specificity 95%.
conclusionThe frequency of enostosis in this study is 89%. The average density identified can help to distinguish enostoses from UOM. ADVANCES IN KNOWLEDGE: We report the exact frequency of enostosis.
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