Evidence map›Paper›PMID 31469289›Full record

ArticleThe British journal of radiology2019

Clinical value of a new generation adaptive statistical iterative reconstruction (ASIR-V) in the diagnosis of pulmonary nodule in low-dose chest CT.

Hui Tang, Zhentang Liu, Zhijun Hu, Taiping He, Dou Li, Nan Yu, Yongjun Jia, Hong Shi

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in The British journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hui TangDepartment of Radiology, Xi'an No.1 Hospital, Xi'an, Shaanxi, China.
Zhentang LiuDepartment of Radiology, Chang'an Hospital, Xi'an, Shaanxi, China.
Zhijun HuDepartment of Radiology, Chang'an Hospital, Xi'an, Shaanxi, China.
Taiping HeDepartment of Radiology, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China.
Dou LiDepartment of Radiology, Chang'an Hospital, Xi'an, Shaanxi, China.
Nan YuDepartment of Radiology, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China.
Yongjun JiaDepartment of Radiology, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China.
Hong ShiDepartment of Radiology, Xi'an No.1 Hospital, Xi'an, Shaanxi, China.
Affiliated Hospital of Shaanxi University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the clinical value of low-dose chest CT combined with the new generation adaptive statistical iterative reconstruction (ASIR-V) algorithm in the diagnosis of pulmonary nodule.

methods30 patients with pulmonary nodules underwent chest CT using Revolution CT. The patients were first scanned with standard-dose at a noise index (NI) of 14, and the images were reconstructed with filtered back projection (FBP) algorithm. If pulmonary nodules were found, a low-dose targeted scan, with NI of 24, was performed localized on the nodules, and the images were reconstructed with 60% ASIR-V. The detection rate of pulmonary nodules in the two scanning modes was recorded. The size of nodules, CT value and standard deviation of nodules were measured. The signal-to-noise ratio and contrast-to-noise ratio were also calculated. Two experienced radiologists used a 5-point method to score the image quality. The volumetric CT dose index, and dose-length product were recorded and the effective dose (ED) was calculated of the two scanning modes.

resultsVolumetric CT dose index (ED) of the standard-dose scan covering the entire lungs was 7.29 ± 2.38 mGy (3.52 ± 1.09 mSv), and that of low-dose targeted scan was 2.56 ± 1.87 mGy (0.51 ± 0.32 mSv). However, the ED of the virtual low-dose scan for the entire lungs was 1.44 ± 0.15 mSv, which would mean a dose reduction of 59.1% compared with the standard-dose scan. 85 of the 87 pulmonary nodules were detected in the low-dose targeted scan, with 2 of the ground-glass density nodules with size less than 1 cm missed, resulting in 97.7% overall detection rate. There was no difference between the low-dose ASIR-V images and standard-dose FBP images for the size (1.49 ± 0.74 cm

conclusionThe low-dose CT scan combined with ASIR-V algorithm is of comparable value in the detection and the display of pulmonary nodules when compared with the FBP images obtained by standard-dose scan. ADVANCES IN KNOWLEDGE: This is a clinical study to evaluate the clinical value of pulmonary nodules using ASIR-V algorithm in the same patients in the low-dose chest CT scans. It suggests that ASIR-V provides similar image quality and detection rate for pulmonary nodules at much reduced radiation dose.

Indexed as

AdolescentAdultAgedAged, 80 and overAlgorithmsFemaleHumansMaleMiddle AgedMultiple Pulmonary NodulesRadiation DosageRadiographic Image Interpretation, Computer-AssistedSignal-To-Noise RatioTomography, X-Ray ComputedYoung Adult

Identifiers

PMID31469289
PMCPMC6849666
OpenAlexW2971198564

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.