Evidence map›Paper›PMID 31468332›Full record

ReviewJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2020

Clinical Utility of Autologous Salvaged Blood: a Review.

Steven M Frank, Robert A Sikorski, Gerhardt Konig, Diamantis I Tsilimigras, Jan Hartmann, Mark A Popovsky, Timothy M Pawlik, Jonathan H Waters

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Feasibility and effectiveness of the novel HemoClear microfiltration cell-salvage system in cesarean sections in South Africa.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Intraoperative cell salvage technique in patients undergoing complex endovascular aortic repair.Journal of vascular surgery cases and innovative techniques · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Turbulence in surgical suction heads as detected by MRI.The journal of extra-corporeal technology · 2023
    Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Steven M FrankJohns Hopkins Health System Blood Management Program, Armstrong Institute for Patient Safety and Quality, Department of Anesthesiology/Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Robert A SikorskiDepartment of Anesthesiology/Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Gerhardt KonigDepartment of Anesthesiology & Bioengineering, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Diamantis I TsilimigrasDepartment of Surgery, The Ohio State University Wexner Medical Center, 395 W. 12th Ave., Suite 670, Columbus, OH, USA.
Jan HartmannHaemonetics Corporation, Braintree, MA, USA.
Mark A PopovskyHaemonetics Corporation, Braintree, MA, USA.
Timothy M PawlikDepartment of Surgery, The Ohio State University Wexner Medical Center, 395 W. 12th Ave., Suite 670, Columbus, OH, USA. tim.pawlik@osumc.edu.ORCID 0000-0002-4828-8096
Jonathan H WatersDepartment of Anesthesiology & Bioengineering, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAutologous salvaged blood, commonly referred to as "cell saver" or "cell salvage" blood, is an important method of blood conservation. Understanding the mechanism of action and summarizing the existing evidence regarding the safety, efficiency, and the relative costs of cell salvage may help educate clinicians on how and when to best utilize autotransfusion.

methodsThis review focuses on issues concerning the quality of red blood cells (RBC), efficiency, and the cost effectiveness relative to autotransfusion. The key considerations of safe use and clinical applicability are described along with the challenges for wider dissemination.

resultsCell salvage can reduce requirements for allogeneic transfusions, along with the associated risks and costs. Autologous salvaged RBCs provide high-quality transfusion, since the cells have not been subjected to the adverse effects of storage as occurs with banked blood. The risks for RBC alloimmunization and transfusion-related infectious diseases are also avoided. With a careful selection of cases, salvaged blood can be more cost effective than donor blood. Cell salvage may have a role in cardiac, major vascular, orthopedic, transplant, and trauma surgeries. However, there remain theoretical safety concerns in cases with bacterial contamination or in cancer surgery.

conclusionIn addition to other methods of blood conservation used in patient blood management programs, autologous salvaged blood adds value and is cost effective for appropriate surgical cases. Evidence suggests that autologous salvaged blood may be of higher quality and confer a cost reduction compared with the allogeneic banked blood, when used appropriately.

Indexed as

Blood Transfusion, AutologousErythrocytesOperative Blood SalvageBlood Loss, SurgicalCost-Benefit AnalysisHumansIntraoperative CareAutologous bloodCell salvageCell saverTransfusion

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.