Evidence map›Paper›PMID 31468267›Full record

ReviewDigestive diseases and sciences2019

Current Controversies Concerning Capsule Endoscopy.

David R Cave, Shahrad Hakimian, Krunal Patel

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Digestive diseases and sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05249933 (The Efficiency of Pronase Granules in Gastric Cleaning of Magnetically Controlled Capsule Endoscopy), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05249933 phase2 / phase3unknown statusnot on this mapstarted 2021, after this paper: background citation

The Efficiency of Pronase Granules in Gastric Cleaning of Magnetically Controlled Capsule Endoscopy: a Prospective Randomized Controlled Study

TypeinterventionalSponsorChanghai HospitalRan2021 to 2022Enrolled290ConditionsGastric Disease, Capsule EndoscopyArmsDeyou, Beijing Tide Pharmaceutical Co, China, containing 20,000 iu pronase granules combined with 1 g NaHCO3 to maintain the intragastric PH at 6-8
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Capsule endoscopy in airway: a difficult extraction.Journal of surgical case reports · 2022
    Article
  6. Capsule endoscopy with retention of 4 years: A case report.International journal of surgery case reports · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

David R CaveDivision of Gastroenterology, Department of Medicine, The University of Massachusetts, 55 Lake Avenue North, Worcester, MA, 01655, USA. David.cave@umassmemorial.org.
Shahrad HakimianDivision of Gastroenterology, Department of Medicine, The University of Massachusetts, 55 Lake Avenue North, Worcester, MA, 01655, USA.
Krunal PatelDivision of Gastroenterology, Department of Medicine, The University of Massachusetts, 55 Lake Avenue North, Worcester, MA, 01655, USA.
University of Massachusetts Chan Medical School · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Video capsule endoscopy became a reality in 2001. This device enabled us to directly view the mucosa of the small intestine for the first time. The main indications for the video capsule remain the detection of small intestinal bleeding and iron deficiency anemia, diagnosis and management of Crohn's disease, and detection of tumors. The device is extraordinarily safe and can be used in the very young to the very old. However, there remain several areas of controversy and difficulty. These are covered in this article and include details of indications and contraindications, whether to prepare patients, whether or not to use simethicone and prokinetics. Detection of location of the capsule remains a major engineering challenge. Reading the videos reliably and quickly remains challenging. However, artificial intelligence and machine learning are already on the horizon to provide assistance. New uses for capsule endoscopy promise more accurate diagnosis and hence improved management of acute gastrointestinal bleeding. The colon capsule may eventually help those who refuse conventional colonoscopy, and robotically controlled capsules may be helpful in screening for serious disease in patients with upper abdominal complaints. The advent of the broadening use of video capsule endoscopy is, though it will be controversial, embraced by some and derided by others; such is the nature of technological development. In the long run, if the use of the video capsule, based on sound evidence-based studies, can be shown to improve the care of our patients and reduce the cost of health care, its use will continue to expand.

Indexed as

Capsule EndoscopyEndoscopy, GastrointestinalHumansIntestinal DiseasesIntestine, SmallControversiesIndicationsSmall intestineVideo capsule endoscopy

Identifiers

PMID31468267
OpenAlexW2970891731

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.