Evidence map›Paper›PMID 31468234›Full record

ReviewJournal of industrial microbiology & biotechnology2019

Microbial production of 2,3-butanediol for industrial applications.

Chan Woo Song, Jong Myoung Park, Sang Chul Chung, Sang Yup Lee, Hyohak Song

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of industrial microbiology & biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Review
  2. Article
  3. Endogenous Ethanol Metabolism and Development of MASLD-MASH.International journal of molecular sciences · 2025
    Review
  4. Key findings from 15 years ofApplied and environmental microbiology · 2025
    Review
  5. Article
  6. From fossil-based to circular bioeconomy: a Swedish and Finnish pathway.Environmental science and pollution research international · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Metabolic engineering ofApplied and environmental microbiology · 2024
    Article
  13. Article
  14. Article
  15. NMR-Based Metabolomic Study onMolecules (Basel, Switzerland) · 2023
    Article
  16. Article
  17. Identification of natural CTXM-15 inhibitors from aqueous extract of endophytic bacteria Cronobactersakazaki.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chan Woo SongResearch and Development Center, GS Caltex Corporation, Yuseong-gu, Daejeon, 34122, South Korea.
Jong Myoung ParkResearch and Development Center, GS Caltex Corporation, Yuseong-gu, Daejeon, 34122, South Korea.
Sang Chul ChungResearch and Development Center, GS Caltex Corporation, Yuseong-gu, Daejeon, 34122, South Korea.
Sang Yup LeeDepartment of Chemical and Biomolecular Engineering (BK21 Plus Program), BioProcess Engineering Research Center, Bioinformatics Research Center, Korea Advanced Institute of Science and Technology, Daejeon, 34141, South Korea.
Hyohak SongResearch and Development Center, GS Caltex Corporation, Yuseong-gu, Daejeon, 34122, South Korea. hyohaks@gscaltex.com.ORCID http://orcid.org/0000-0001-7376-6355

Funding

MOTIE, Korea No. 10050407
6 · The paper itself

Abstract

2,3-Butanediol (2,3-BD) has great potential for diverse industries, including chemical, cosmetics, agriculture, and pharmaceutical areas. However, its industrial production and usage are limited by the fairly high cost of its petro-based production. Several bio-based 2,3-BD production processes have been developed and their economic advantages over petro-based production process have been reported. In particular, many 2,3-BD-producing microorganisms including bacteria and yeast have been isolated and metabolically engineered for efficient production of 2,3-BD. In addition, several fermentation processes have been tested using feedstocks such as starch, sugar, glycerol, and even lignocellulose as raw materials. Since separation and purification of 2,3-BD from fermentation broth account for the majority of its production cost, cost-effective processes have been simultaneously developed. The construction of a demonstration plant that can annually produce around 300 tons of 2,3-BD is scheduled to be mechanically completed in Korea in 2019. In this paper, core technologies for bio-based 2,3-BD production are reviewed and their potentials for use in the commercial sector are discussed.

Indexed as

BacteriaButylene GlycolsFermentationGlycerolLigninMetabolic Engineering2,3-butylene glycolButylene GlycolsGlycerolLigninlignocellulose2,3-ButanediolCommercial sectorFermentationMetabolic engineeringSeparation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.