Evidence map›Paper›PMID 31468061›Full record

ArticlePediatric cardiology2019

Acute Hemodynamic Effects of Negative Extrathoracic Pressure in Fontan Physiology.

David M Peng, Jeffrey D Zampi, Susan M Smith, Sunkyung Yu, Nichole Rottach, Ray Lowery, Heang M Lim, Lori Q Riegger, Kurt R Schumacher, Albert Rocchini

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Pediatric cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05240989 (Correlation Between Pulmonary Rehabilitation and Thoracic Fluid Capacity), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05240989 unknown statusnot on this mapstarted 2021, after this paper: background citation

Correlation Between Pulmonary Rehabilitation and Thoracic Fluid Capacity: One-year Follow-up of Observation Research

TypeobservationalSponsorFu Jen Catholic UniversityRan2021 to 2023Enrolled25ConditionsCOPD Received PRArmspulmonary rehabilitation
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

David M PengUniversity of Michigan Congenital Heart Center, 1540 East Hospital Drive, Ann Arbor, MI, 48109, USA. davepeng@med.umich.edu.ORCID http://orcid.org/0000-0001-7763-7518
Jeffrey D ZampiUniversity of Michigan Congenital Heart Center, 1540 East Hospital Drive, Ann Arbor, MI, 48109, USA.
Susan M SmithUniversity of Michigan Congenital Heart Center, 1540 East Hospital Drive, Ann Arbor, MI, 48109, USA.
Sunkyung YuUniversity of Michigan Congenital Heart Center, 1540 East Hospital Drive, Ann Arbor, MI, 48109, USA.
Nichole RottachUniversity of Michigan Congenital Heart Center, 1540 East Hospital Drive, Ann Arbor, MI, 48109, USA.
Ray LoweryUniversity of Michigan Congenital Heart Center, 1540 East Hospital Drive, Ann Arbor, MI, 48109, USA.
Heang M LimUniversity of Michigan Congenital Heart Center, 1540 East Hospital Drive, Ann Arbor, MI, 48109, USA.
Lori Q RieggerUniversity of Michigan Congenital Heart Center, 1540 East Hospital Drive, Ann Arbor, MI, 48109, USA.
Kurt R SchumacherUniversity of Michigan Congenital Heart Center, 1540 East Hospital Drive, Ann Arbor, MI, 48109, USA.
Albert RocchiniUniversity of Michigan Congenital Heart Center, 1540 East Hospital Drive, Ann Arbor, MI, 48109, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We sought to assess acute hemodynamic changes after implementation of negative extrathoracic pressure (NEP) in spontaneously breathing ambulatory Fontan patients with symptomatic heart failure. We hypothesized that application of NEP would result in an acute decrease in pulmonary artery pressure. Ten patients with clinical evidence of Fontan failure underwent baseline hemodynamic catheterization while breathing spontaneously. Hemodynamic measurements were then repeated after 30 min of continuous NEP. After 30 min of continuous NEP, 4/10 patients had a decrease in their Fontan pressure by 2 mmHg and one patient had a decrease by 1 mmHg. There were three patients that had an increase in Fontan pressure by 2 mmHg. In 7/10 patients, indexed pulmonary vascular resistance decreased by an average of 31%. In symptomatic Fontan patients with a favorable hemodynamic response to NEP during catheterization, potential benefit of longer-term NEP to improve clinical status should be explored.

Indexed as

Ventilators, Negative-PressureAdolescentAdultChildFemaleFontan ProcedureHeart FailureHemodynamicsHumansMalePilot ProjectsRespiration, ArtificialYoung AdultCuirass ventilationFontanHeart failureNegative extrathoracic pressureNegative pressure ventilation

Identifiers

PMID31468061

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.