ReviewJACC. Basic to translational science2019
Neuromodulation for the Treatment of Heart Rhythm Disorders.
Review in JACC. Basic to translational science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Anthracycline-induced arrhythmias in breast cancer therapy: A meta-analysis of single-arm trials.PloS one · 2024Pooled it
- Non-invasive Autonomic Neuromodulation Is Opening New Landscapes for Cardiovascular Diseases.Frontiers in physiology · 2020Pooled it
- Association Between Temperature Management Using Passive Thermal Insulation and a Modified Aldrete Score During Cryoablation of Paroxysmal Atrial Fibrillation Under General Anesthesia.Journal of arrhythmia · 2026Article
- Cardioprotective effects of right stellate ganglion block combined with dexmedetomidine in rats with atrial fibrillation-like atrial tachyarrhythmia.BMC cardiovascular disorders · 2026Article
- Autonomic Nervous Dysfunction and Ultra-Short-Term Heart Rate Variability in Atrial Fibrillation: Recent Advances in Early Detection.Journal of cardiovascular development and disease · 2026Review
- Therapeutic Potential of Heparin/Digoxin Encapsulated Polymeric Nanoparticles: Modulation of Arrhythmias and Neuroinflammation Using Low-Intensity Pulsed Ultrasound on in Vitro and in Vivo Efficacy.Applied biochemistry and biotechnology · 2026Article
- Neural Regulation of Cardiac Arrhythmias: From the Brain-Heart Axis to Emerging Precision Therapies.Research (Washington, D.C.) · 2026Review
- Autonomic nervous system modulation in arrhythmias: mechanisms and therapeutic advances.Frontiers in physiology · 2026Review
- Enhanced Neuromodulation Using PC-CNTs and NIR Photothermal Therapy for Preventing Ventricular Arrhythmias.International journal of nanomedicine · 2026Article
- Advances in the clinical application of stellate ganglion block for non-pain indications.Frontiers in medicine · 2026Review
- Hydrogen Peroxide-Induced Re-Expression of Repressor Element 1-Silencing Transcription Factor Contributes to Cardiac Vagal Dysfunction in Type 2 Diabetes Mellitus.Antioxidants (Basel, Switzerland) · 2025Article
- Catheter Ablation for Vasovagal Syncope: The Therapeutic Potential of Gateway Plexi.Arrhythmia & electrophysiology review · 2025Review
- Non-invasive Neuromodulation of Arrhythmias.Cardiac electrophysiology clinics · 2024Review
- Effect of Ticagrelor Versus Clopidogrel After Off-Pump Coronary Artery Bypass Grafting on Postoperative Atrial Fibrillation: A Cohort Study.Journal of the American Heart Association · 2024Article
- Article
- Novel laparoscopic renal denervation immediately reduces atrial fibrillation inducibility: a swine model study.Scientific reports · 2023Article
- Stellate ganglion ablation by conventional radiofrequency in patients with electrical storm.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Neuromodulation therapy for atrial fibrillation.Heart rhythm · 2023Review
- Long-term outcome after thoracoscopic cardiac sympathectomy for refractory ventricular tachyarrhythmia storm.BMJ case reports · 2022Article
- Research Opportunities in Autonomic Neural Mechanisms of Cardiopulmonary Regulation: A Report From the National Heart, Lung, and Blood Institute and the National Institutes of Health Office of the Director Workshop.JACC. Basic to translational science · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
There is an increasing recognition of the importance of interactions between the heart and the autonomic nervous system in the pathophysiology of arrhythmias. These interactions play a role in both the initiation and maintenance of arrhythmias and are important in both atrial and ventricular arrhythmia. Given the importance of the autonomic nervous system in the pathophysiology of arrhythmias, there has been notable effort in the field to improve existing therapies and pioneer additional interventions directed at cardiac-autonomic targets. The interventions are targeted to multiple and different anatomic targets across the neurocardiac axis. The purpose of this review is to provide an overview of the rationale for neuromodulation in the treatment of arrhythmias and to review the specific treatments under evaluation and development for the treatment of both atrial fibrillation and ventricular arrhythmias.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.