Evidence map›Paper›PMID 31467924›Full record

ArticleBioMed research international2019

Evaluation of Red Cell Distribution Width to Lymphocyte Ratio as Potential Biomarker for Detection of Colorectal Cancer.

Jiahao Huang, Yang Zhao, Lin Liao, Shun Liu, Shaolong Lu, Changtao Wu, Chuanyi Wei, Shaoqiang Xu, Huage Zhong, Junjie Liu and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05341037 (A Novel Biomarker for the Prediction of Early Comorbidity in Cardiac Surgery), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05341037 completednot on this mapstarted 2022, after this paper: background citation

A Novel Biomarker for the Prediction of Early Comorbidity in Cardiac Surgery: Red Cell Distribution With to Lymphocyte Ratio

TypeobservationalSponsorAnkara City Hospital BilkentRan2022 to 2022Enrolled700ConditionsCardiac Surgery
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jiahao HuangDepartment of Gastrointestinal Surgery, Guangxi Clinical Research Center for Colorectal Cancer, Affiliated Tumor Hospital, Guangxi Medical University, Nanning, Guangxi, China.
Yang ZhaoDepartment of Radiology, Affiliated Cancer Hospital, Guangxi Medical University, Nanning, Guangxi, China.
Lin LiaoDepartment of Clinical Laboratory, The First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China.ORCID https://orcid.org/0000-0003-3492-321X
Shun LiuDepartment of Epidemiology, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.
Shaolong LuDepartment of Hepatobiliary Surgery, Affiliated Cancer Hospital, Guangxi Medical University, Nanning, Guangxi, China.
Changtao WuDepartment of Colorectal and Anal Surgery, The First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China.
Chuanyi WeiDepartment of Gastrointestinal Surgery, Guangxi Clinical Research Center for Colorectal Cancer, Affiliated Tumor Hospital, Guangxi Medical University, Nanning, Guangxi, China.
Shaoqiang XuDepartment of General Surgery, Red Cross Hospital of Yulin City, Yulin, Guangxi, China.
Huage ZhongDepartment of Gastrointestinal Surgery, Guangxi Clinical Research Center for Colorectal Cancer, Affiliated Tumor Hospital, Guangxi Medical University, Nanning, Guangxi, China.
Junjie LiuDepartment of Ultrasound, Affiliated Tumor Hospital, Guangxi Medical University, Nanning, Guangxi, China.
Yun GuoDepartment of Colorectal and Anal Surgery, The First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China.
Sen ZhangDepartment of Colorectal and Anal Surgery, The First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China.
Feng GaoDepartment of Colorectal and Anal Surgery, The First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China.
Weizhong TangDepartment of Gastrointestinal Surgery, Guangxi Clinical Research Center for Colorectal Cancer, Affiliated Tumor Hospital, Guangxi Medical University, Nanning, Guangxi, China.ORCID https://orcid.org/0000-0003-0877-8557

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimColorectal cancer (CRC) is the third most lethal cancer globally. This study sought to determine the feasibility of using red cell distribution width-to-lymphocyte ratio (RLR) as a tool to facilitate CRC detection.

methodsSeventy-eight healthy controls, 162 patients diagnosed with CRC, and 94 patients with colorectal polyps (CP) from June 2017 to October 2018 were retrospectively reviewed. Clinical data were obtained to analyze preoperative RLR level, and receiver operating characteristic (ROC) curve analysis was performed to estimate the potential role of RLR as a CRC biomarker.

resultsRLR was higher in patients with CRC than in healthy participants (

conclusionsRLR might serve as a potential biomarker for CRC diagnosis.

Indexed as

AgedAntigens, Tumor-Associated, CarbohydrateBiomarkers, TumorCarcinoembryonic AntigenColorectal NeoplasmsEarly Detection of CancerErythrocyte IndicesFemaleHumansLymphocytesMaleMiddle AgedAntigens, Tumor-Associated, CarbohydrateBiomarkers, Tumorcarbohydrate antigen 199, humanCarcinoembryonic Antigen

Identifiers

PMID31467924
PMCPMC6699340

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.