ArticleBioMed research international2019
An Angle Compared Index with Hybrid of Changes in the Ratio and Amplitude for Quantitative Evaluation of Disease Risk, Biological Function, and Biomarker Efficacy.
Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- A new pathway for considering trigger factors based on parallel-serial connection models and displaying the relationships of causal factors in low-probability events.BMC medical research methodology · 2023Article
- Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this study was to describe variations of different cardinal frequency by using angle compared index (ACI).
methodsThe basic principle of the analysis model is to comprehensively consider changes in both the ratio and absolute value as follows: ACI = arctan {Pd⁎(1-Pc) / [Pc⁎(1-Pd)]} + arctan (Pd - Pc) - 45, where Pd represent percentage of disease occurrence in disease group and Pc represent that in control group. The range of ACI was (0~90). Thus, ACIs from different cardinal frequency are comparable.
resultsWhen biomarkers with similar ratio value, absolute value, or ACI but different positive frequencies were combined, although three indexes (ratio value, absolute value, or ACI) increased after two single biomarkers were combined, only ACI increased with similar amplitudes after two single biomarkers with the same ACI at different positive frequencies were combined.
conclusionThe ACI provides a better understanding power of biomarker and may be a relatively good index for evaluating the complex events represented by different cardinal frequency from new systems.
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