ArticleJournal of clinical & translational endocrinology2019
Type 2 Diabetes Mellitus non-surgical remission: A possible mission.
Article in Journal of clinical & translational endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Use of CT-derived non-cardiovascular calcification marker for predicting cardiovascular events among diabetic older adults: the multi-ethnic study of atherosclerosis.European radiology · 2026Article
- Type 2 diabetes remission: multidimensional pharmacological strategies and future perspectives.Frontiers in endocrinology · 2025Review
- A 5-structured visits multidisciplinary clinical care approach to optimize the care of patients with type 2 diabetes: a pilot study.Cardiovascular endocrinology & metabolism · 2023Article
- Cortisol/DHEA ratio in morbidly obese patients before and after bariatric surgery: Relation to metabolic parameters and cardiovascular performance.International journal of obesity (2005) · 2022Article
- Dissonance in the discourse of the duration of diabetes: A mixed methods study of patient perceptions and clinical practice.Health expectations : an international journal of public participation in health care and health policy · 2021Article
- A set of miRNAs predicts T2DM remission in patients with coronary heart disease: from the CORDIOPREV study.Molecular therapy. Nucleic acids · 2021Article
- How Family Physicians Practice the Principle of Remission Along the Glycemic Continuum.Journal of primary care & community healthArticle
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2 authors.
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Abstract
backgroundRemission of Type 2 Diabetes Mellitus (DM) has been observed throughout the last few years, yet factors associated with remission through non-surgical approaches are still unclear. So, the factors associated with type 2 DM remission were investigated.
methodsOut 670 patients, 63 patients gained non-surgical remission of type 2 DM (defined according to ADA criteria), and 396 patients served as control matched for age, sex, and BMI. The records of patients who attended Alexandria University Students Hospital between the years 2015 and 2018 were reviewed retrospectively. The collected data at first visit and 1 year after remission were history, examination, HbA1c %, oral glucose tolerance test & fasting blood glucose and lipid profile and type of treatment.
results75% of patients were females with mean age 51.5 ± 11.34 years. The mean duration of treatment till remission was 26.4 ± 33.1 months. One year after remission HbA1c & BMI were significantly decreased (P = 0.001, 0.03; respectively). However, cox proportional hazards model & ROC curve analysis showed that age < 50 years, female sex, short duration of diabetes < 5.2 years, intial HbA1c < 8.5%, HDL > 45.6 mg/dl, and initial intervention with lifestyle modification, 2000 mg metformin and 100 mg vildagliptin are the factors associated with remission.
conclusionOur mission in type 2 DM female patients < 50 years with short duration of disease < 5.2 years, initial HbA1c < 8.5% and HDL > 45.6 mg/dl, is to achieve diabetes remission by intensive life style modification with daily metformin and vildagliptin.
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