ArticleMobile DNA2019
Characterization of the endogenous retrovirus insertion in
Article in Mobile DNA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- A review of genetic variation underlying chicken phenotypic diversity.Poultry science · 2025Review
- Impact of the 294 bp SINE Insertion in 5'UTR of theAnimals : an open access journal from MDPI · 2025Article
- Endogenous retrovirus loci and induced changes in gene expression in Japanese indigenous chickens.Scientific reports · 2025Article
- Genome-wide characterization and comparison of endogenous retroviruses among 3 duck reference genomes.Poultry science · 2024Article
- Article
- Transcriptome Sequencing Reveals That Intact Expression of the Chicken Endogenous RetrovirusAnimals : an open access journal from MDPI · 2023Article
- SINE Insertion in the Pig Carbonic Anhydrase 5BAnimals : an open access journal from MDPI · 2023Article
- Two Retrotransposon Elements in Intron of PorcineLife (Basel, Switzerland) · 2022Article
- Allele-biased expression of the bovine APOB gene associated with the cholesterol deficiency defect suggests cis-regulatory enhancer effects of the LTR retrotransposon insertion.Scientific reports · 2022Article
- Molecular genetic variation of animals and plants under domestication.Proceedings of the National Academy of Sciences of the United States of America · 2022Review
- Retrotransposon Insertion Polymorphisms (RIPs) in Pig Coat Color Candidate Genes.Animals : an open access journal from MDPI · 2022Article
- Fourth Report on Chicken Genes and Chromosomes 2022.Cytogenetic and genome research · 2022Review
- A 192 bp ERV fragment insertion in the first intron of porcine TLR6 may act as an enhancer associated with the increased expressions of TLR6 and TLR1.Mobile DNA · 2021Article
- Falling fowl of the chicken reference genome: pitfalls of studying polymorphic endogenous retroviruses.Retrovirology · 2021Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHenny feathering in chickens is determined by a dominant mutation that transforms male-specific plumage to female-like plumage. Previous studies indicated that this phenotype is caused by ectopic expression in skin of
resultsWe used publicly available whole genome sequence data to determine the flanking sequences of the ERV, and then PCR amplified the entire insertion and sequenced it using Nanopore long reads and Sanger sequencing. The 7524 bp insertion contains an intact endogenous retrovirus that was not found in chickens representing 31 different breeds not showing henny feathering or in samples of the ancestral red junglefowl. The sequence shows over 99% sequence identity to the avian leukosis virus ev-1 and ev-21 strains, suggesting a recent integration. The ERV 3'LTR, containing a powerful transcriptional enhancer and core promoter with TATA box together with binding sites for EFIII and Ig/EBP inside the
conclusionsWe demonstrate that the henny feathering allele harbors an insertion of an intact avian leukosis virus at the 5'end of
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.