Evidence map›Paper›PMID 31467527›Full record

ArticleInternational journal of endocrinology2019

Gastroenteropancreatic Neuroendocrine Neoplasia Characterization in Portugal: Results from the NETs Study Group of the Portuguese Society of Endocrinology, Diabetes and Metabolism.

A P Santos, J Vinagre, P Soares, I Claro, A C Sanches, L Gomes, I Fernandes, A L Catarino, J Preto, B D Pereira and 9 more

Erratum issuedAbstract read
In one paragraph

Article in International journal of endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

A P SantosInstituto Português de Oncologia do Porto, Francisco Gentil (IPOPFG), 4200-162 Porto, Portugal.ORCID https://orcid.org/0000-0002-8896-305X
J VinagreInstituto de Investigação e Inovação em Saúde (i3S), 4200-135 Porto, Portugal.ORCID https://orcid.org/0000-0002-0871-1427
P SoaresInstituto de Investigação e Inovação em Saúde (i3S), 4200-135 Porto, Portugal.ORCID https://orcid.org/0000-0001-9607-6998
I ClaroCentro Hospitalar de Lisboa Ocidental (CHLO), 1349-019 Lisboa, Portugal.
A C SanchesInstituto Português de Oncologia do Porto, Francisco Gentil (IPOPFG), 4200-162 Porto, Portugal.
L GomesCentro Hospitalar e Universitário de Coimbra (CHUC), 3000-075 Coimbra, Portugal.
I FernandesCentro Hospitalar Lisboa Norte, EPE (CHLN), 1649-035 Lisboa, Portugal.
A L CatarinoHospital da Luz, 1500-650 Lisboa, Portugal.
J PretoFaculdade de Medicina da Universidade do Porto (FMUP), 4200-319 Porto, Portugal.
B D PereiraHospital Garcia de Orta, EPE, 2801-951 Almada, Portugal.
A P MarquesUnidade Local de Saúde de Matosinhos, 4464-513 Senhora da Hora, Portugal.
F RodriguesInstituto Português de Oncologia de Coimbra, Francisco Gentil (IPOCFG), 3000-075 Coimbra, Portugal.
C AmaralCentro Hospitalar do Porto-Hospital Santo António, 4099-001 Porto, Portugal.
G RochaCentro Hospitalar Gaia/Espinho (CHGE), 4434-502 Vila Nova de Gaia, Portugal.
J C MellidezCentro Hospitalar do Baixo Vouga (CHBV), 3810-501 Aveiro, Portugal.
H SimõesCentro Hospitalar de Lisboa Ocidental (CHLO), 1349-019 Lisboa, Portugal.
J M LopesInstituto de Investigação e Inovação em Saúde (i3S), 4200-135 Porto, Portugal.ORCID https://orcid.org/0000-0001-8597-3474
M J BugalhoCentro Hospitalar Lisboa Norte, EPE (CHLN), 1649-035 Lisboa, Portugal.
On behalf of the NETs Study Group of the Portuguese Society of Endocrinology, Diabetes and Metabolism

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) has been increasing in the last five decades, but there is no large-scale data regarding these tumours in Portugal. We conducted a cross-sectional, multicentric study in main Portuguese centers to evaluate the clinical, pathological, and therapeutic profile of GEP-NENs.

methodsFrom November, 2012, to July, 2014, data from 293 patients diagnosed with GEP-NENs from 15 centers in Portugal was collected and registered in an online electronic platform.

resultsMedian age at diagnosis was 56.5 (range: 15-87) years with a preponderance of females (54.6%). The most frequent primary sites were the pancreas (31.1%), jejunum-ileum (24.2%), stomach (13.7%), and rectum (8.5%). Data regarding hormonal status was not available in most patients (82.3%). Stratified by the tumour grade (WHO 2010 classification), we observed 64.0% of NET G1, 24.7% of NET G2, and 11.3% of NEC. Poorly differentiated tumours occurred mainly in older patients (

conclusionIn general, Portuguese patients with GEP-NENs presented similar characteristics to other populations described in the literature. This cross-sectional study represents the first step to establish a national database of GEP-NENs that may aid in understanding the clinical and epidemiological features of these tumours in Portugal.

Identifiers

PMID31467527
PMCPMC6701412

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.