ReviewGastroenterology research and practice2019
Diagnosing Celiac Disease: Towards Wide-Scale Screening and Serology-Based Criteria?
Review in Gastroenterology research and practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Screen-Detected Coeliac Disease in a Nationally Representative Cohort: Health Indicators, Long-Term Outcomes and Mortality.Alimentary pharmacology & therapeutics · 2026Article
- The needle study: Machine learning as a new method for case-finding in celiac disease.Journal of pediatric gastroenterology and nutrition · 2026Article
- Autoimmune Polyendocrine Syndromes in Adult Italian Celiac Disease Patients.Journal of clinical medicine · 2024Article
- Gluten-free diet adherence in children with screening-detected celiac disease using a prospective birth cohort study.PloS one · 2023Article
- Population-based screening for celiac disease reveals that the majority of patients are undiagnosed and improve on a gluten-free diet.Scientific reports · 2022Article
- Article
- The global burden of coeliac disease: opportunities and challenges.Nature reviews. Gastroenterology & hepatology · 2022Review
- Validation of the X-ray microtomography in the assessment of duodenal morphometry and surface area in celiac disease.Frontiers in immunology · 2022Article
- May Antitransglutaminase Levels Predict Severity of Duodenal Lesions in Adults with Celiac Disease?Medicina (Kaunas, Lithuania) · 2021Article
- Coeliac disease is associated with depression in children and young adults with type 1 diabetes: results from a multicentre diabetes registry.Acta diabetologica · 2021Article
- Article
- Article
- Case Report: Cerebral venous thrombosis revealing celiac disease.F1000Research · 2021Article
- Celiac Disease and Obesity: Is Bariatric Surgery an Option?Obesity surgery · 2020Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Celiac disease is one of the most common food-related chronic disorders in children. Unfortunately, this multifaceted disease is challenging to recognize and remains markedly underdiagnosed. Screening of either known at-risk groups or even the whole population could increase the suboptimal diagnostic yield substantially. Many recent guidelines recommend screening of at least selected risk groups, but more wide-scale screening remains controversial. The increasing prevalence of celiac disease and the development of autoantibody assays have also led to a gradual shift in the diagnostics towards less invasive serology-based criteria in a subgroup of symptomatic children. The main open questions concern whether these criteria are applicable to all countries and clinical settings, as well as to adult patients. On the other hand, widening screening and the mistaken practice of initiating a gluten-free diet before the appropriate exclusion of celiac disease increase the number of borderline seropositive cases, which may also challenge the classical histopathological diagnostics. Sophisticated diagnostic methods and a deeper understanding of the natural history of early developing celiac disease may prove useful in these circumstances.
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Registered trials
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