Evidence map›Paper›PMID 31467513›Full record

ArticleThe journal of venomous animals and toxins including tropical diseases2019

Protein identification from the parotoid macrogland secretion of

Douglas Oscar Ceolin Mariano, Marcela Di Giacomo Messias, Patrick Jack Spencer, Daniel Carvalho Pimenta

Abstract read
In one paragraph

Article in The journal of venomous animals and toxins including tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Douglas Oscar Ceolin MarianoLaboratory of Biochemistry and Biophysics, Butantan Institute, São Paulo, SP, Brazil.
Marcela Di Giacomo MessiasBiotechnology Center, Nuclear and Energy Research Institute (IPEN), São Paulo, SP, Brazil.
Patrick Jack SpencerBiotechnology Center, Nuclear and Energy Research Institute (IPEN), São Paulo, SP, Brazil.
Daniel Carvalho PimentaLaboratory of Biochemistry and Biophysics, Butantan Institute, São Paulo, SP, Brazil.ORCID 0000-0003-2406-0860

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBufonid parotoid macrogland secretion contains several low molecular mass molecules, such as alkaloids and steroids. Nevertheless, its protein content is poorly understood. Herein, we applied a sample preparation methodology that allows the analysis of viscous matrices in order to examine its proteins.

methods

resultsForty-two proteins could be identified, such as acyl-CoA-binding protein, alcohol dehydrogenase, calmodulin, galectin and histone. Moreover,

conclusionsProper sample preparation allowed the proteomic and

Indexed as

Amphibian skin secretionAsian common toadBatch chromatographyBufonidaeDuttaphrynus melanostictusProteomics

Identifiers

PMID31467513
PMCPMC6707386

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.