Evidence map›Paper›PMID 31467495›Full record

ArticleTheScientificWorldJournal2019

Comparison of Trace Elements in High-Molecular-Mass Multiprotein Complex and in Female Milk from Which It Was Obtained.

Svetlana E Soboleva, Natalia P Zaksas, Georgy A Nevinsky

Open access · goldAbstract readComparative Study
In one paragraph

Article in TheScientificWorldJournal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Svetlana E SobolevaInstitute of Chemical Biology and Fundamental Medicine, Siberian Division of Russian Academy of Sciences, Pr. Akademika Lavrentieva 8, Novosibirsk 630090, Russia.
Natalia P ZaksasNikolaev Institute of Inorganic Chemistry, Siberian Division of Russian Academy of Sciences, Pr. Akademika Lavrentieva 3, Novosibirsk 630090, Russia.
Georgy A NevinskyInstitute of Chemical Biology and Fundamental Medicine, Siberian Division of Russian Academy of Sciences, Pr. Akademika Lavrentieva 8, Novosibirsk 630090, Russia.ORCID https://orcid.org/0000-0002-4988-8923
Institute of Chemical Biology and Fundamental Medicine · RUNikolaev Institute of Inorganic Chemistry · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany biological processes are performed by different protein complexes. During the association of proteins and enzymes forming specific complexes, the latter can include ions of various metal ions, which may be important for their formation and biological function. OBJECTIVE OF THE STUDIES: However, to date in the literature there are no data on metal ions that are part of any protein complexes.

methodsA very stable multiprotein complex (~1000±100 kDa) was separated from other proteins of nine samples of female milk by gel filtration on Sepharose 4B. The content of microelements in the stable multiprotein complex and milk was analyzed using two-jet plasma atomic emission spectrometry.

resultsThe content of different elements in milk on average decreased in the order: Ca>P>Mg>Al≥Zn≥Fe>Cu >B (0.76-3500

conclusionsThe analysis of the relative content of sixteen elements in human milk and oligomeric complexes of proteins was performed for the first time. Data on the content of metals indicate that during the formation of protein which associates the increase in the content of metal ions bound with proteins of the complex can occur. Such metal ions can be important for the formation and biological function of protein complexes.

Indexed as

AnimalsFemaleMetalsMilkMolecular WeightMultiprotein ComplexesScattering, RadiationTime FactorsTrace ElementsMetalsMultiprotein ComplexesTrace Elements

Identifiers

PMID31467495
PMCPMC6699245
OpenAlexW2965627782

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.