Evidence map›Paper›PMID 31467454›Full record

ArticleJournal of the Royal Statistical Society. Series C, Applied statistics2019

Landmark Linear Transformation Model for Dynamic Prediction with Application to a Longitudinal Cohort Study of Chronic Disease.

Yayuan Zhu, Liang Li, Xuelin Huang

Abstract read
In one paragraph

Article in Journal of the Royal Statistical Society. Series C, Applied statistics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Yayuan ZhuUniversity of Western Ontario, London, Canada.
Liang LiUniversity of Texas MD Anderson Cancer Center, Houston, USA.
Xuelin HuangUniversity of Texas MD Anderson Cancer Center, Houston, USA.
The University of Texas MD Anderson Cancer Center · USWestern University · CA

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
University of Texas M.D. Anderson Cancer SPORE-LeukemiaP50CA100632 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KONOPLEVA, MARINA Y · 2003 to 2023
$43.7M
UPR/MDACC Partnership for Excellence in Cancer Research (Luis Segarra supplement)U54CA096300 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Susan K Peterson · 2002 to 2026
$23.8M
Comparative Modeling: Informing Breast Cancer Control Practice and PolicyU01CA199218 · NCI · GEORGETOWN UNIVERSITY · PI BERRY, DONALD A, DE KONING, HARRY J · 2015 to 2019
$9.0M
Comparative Modeling: Informing Breast Cancer Control Practice & PolicyU01CA152958 · NCI · GEORGETOWN UNIVERSITY · PI BERRY, DONALD A, DE KONING, HARRY J · 2010 to 2015
$7.6M
Chronic Kidney Disease (CKD) Biomarkers Consortium Data Coordinating CenterU01DK103225 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI SCHRAUBEN, SARAH JEANNE · 2014 to 2020
$5.5M
NCI NIH HHS P30 CA016672NCI NIH HHS P50 CA100632NCI NIH HHS U01 CA152958NCI NIH HHS U01 CA199218NCI NIH HHS U54 CA096300NIDDK NIH HHS U01 DK103225
6 · The paper itself

Abstract

Dynamic prediction of the risk of a clinical event using longitudinally measured biomarkers or other prognostic information is important in clinical practice. We propose a new class of landmark survival models. The model takes the form of a linear transformation model, but allows all the model parameters to vary with the landmark time. This model includes many published landmark prediction models as special cases. We propose a unified local linear estimation framework to estimate time-varying model parameters. Simulation studies are conducted to evaluate the finite sample performance of the proposed method. We apply the methodology to a dataset from the African American Study of Kidney Disease and Hypertension and predict individual patient's risk of an adverse clinical event.

Indexed as

Chronic kidney diseaseLocal-linear estimationLongitudinal biomarkersReal-time predictionSurvival analysis

Identifiers

PMID31467454
PMCPMC6715145
OpenAlexW2906421128

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.