Evidence map›Paper›PMID 31467425›Full record

ArticleLaboratory investigation; a journal of technical methods and pathology2019

The high-density lipoprotein receptor Scarb1 is required for normal bone differentiation in vivo and in vitro.

Irina L Tourkova, Steven F Dobrowolski, Cassandra Secunda, Mone Zaidi, Ioanna Papadimitriou-Olivgeri, Dionysios J Papachristou, Harry C Blair

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Laboratory investigation; a journal of technical methods and pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Preclinical evaluation of ELP-004 in mice.Pharmacology research & perspectives · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. The function of the calcium channel Orai1 in osteoclast development.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
  15. A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow-Fed Young Adult Mice.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2021
    Article
  16. Article
  17. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Irina L TourkovaVeteran's Affairs Medical Center, Pittsburgh, PA, 15206, USA.
Steven F DobrowolskiDepartment of Pathology, University of Pittsburgh, Pittsburgh, PA, 15261, USA.
Cassandra SecundaDepartment of Pathology, University of Pittsburgh, Pittsburgh, PA, 15261, USA.
Mone ZaidiThe Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Ioanna Papadimitriou-OlivgeriDepartment of Anatomy-Histology-Embryology, Unit of Bone and Soft Tissue Studies, University of Patras, School of Medicine, Patras, Greece.
Dionysios J PapachristouDepartment of Pathology, University of Pittsburgh, Pittsburgh, PA, 15261, USA.
Harry C BlairVeteran's Affairs Medical Center, Pittsburgh, PA, 15206, USA. hcblair@pitt.edu.
University of Pittsburgh · USUniversity of Patras · GRIcahn School of Medicine at Mount Sinai · US

Funding

Regulation of Osteoclastogenesis by CalciumR01AR065407 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BLAIR, HARRY COLBERT, ROBINSON, LISA J · 2013 to 2017
$1.6M
Regulation of Osteoclast Activity by Calcium and cGMPR01AR053976 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BLAIR, HARRY COLBERT · 2007 to 2010
$1.1M
BLRD VA I01 BX002490NIAMS NIH HHS R01 AR053976NIAMS NIH HHS R01 AR065407
6 · The paper itself

Abstract

We examined bone formation and turnover in high-density lipoprotein (HDL) receptor, scavenger receptor type I (Scarb1), knockout animals relative to wild-type (WT) controls. Scarb1

Indexed as

Cell DifferentiationOsteoblastsOsteogenesisAdrenocorticotropic HormoneAnimalsBone DensityBone RemodelingFemaleMaleMiceMice, KnockoutOsteoclastsPrimary Cell CultureScavenger Receptors, Class BAdrenocorticotropic HormoneScarb1 protein, mouseScavenger Receptors, Class B

Identifiers

PMID31467425
PMCPMC11715553
OpenAlexW2971311727

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.