ArticleScientific reports2019
Carcinogenic risk of human papillomavirus (HPV) genotypes and potential effects of HPV vaccines in Korea.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Prevalence and genotypes' distribution of human papillomavirus among women in Saudi Arabia: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- The role and diagnostic value of deregulated miRNAs in cervical cancer.Discover oncology · 2025Review
- Analysis of 19,116 cases of human papillomavirus infection and subtype distribution in Sanmen, Zhejiang Province, China.BMC infectious diseases · 2025Article
- Benefits and challenges of cervical cancer screening since the implementation of the 'two cancer' screening programme in China: findings from Shangyu, Zhejiang in 2019-23.Journal of global health · 2025Article
- Development and evaluation of a novel E7 multi-epitopic vaccine for human papillomavirus type 16: design, expression, purification, and immunological characterization.BMC infectious diseases · 2025Article
- HPV Vaccination Program in Indonesia: Effectiveness, Dose, Scale-Up Costs, Future Prospects, and Policy Recommendations.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Assessment of malignant potential for HPV types 16, 52, and 58 in the uterine cervix within a Korean cohort.Scientific reports · 2024Article
- Article
- Characterization of human papillomavirus genotypes and their coverage in vaccine delivered to Ethiopian women.Scientific reports · 2024Article
- Prevalence of cervical high-risk human papillomavirus among Zimbabwean women living with HIV.Southern African journal of HIV medicine · 2024Article
- Human papillomavirus serotypes and determinants among women with invasive cervical cancer in Katsina state, Northwest-Nigeria: a multicentre study.Ecancermedicalscience · 2024Article
- RAP1-GTPase immunostaining is altered in human precancerous and cancerous cervical lesions.Biomarkers in medicine · 2024Article
- A Rapid, Sensitive and Type-Specific Detection of High-Risk HPV-16 and HPV-18.Journal of obstetrics and gynaecology of India · 2023Article
- Do Concurrent Multiple Infections with High-Risk HPVs Carry a More Malignant Potential than a Single Infection in the Uterine Cervix?Journal of clinical medicine · 2023Article
- Human papillomavirus spectrum of HPV-infected women in Nigeria: an analysis by next-generation sequencing and type-specific PCR.Virology journal · 2023Article
- Prevalence of High-Risk Human Papillomavirus Types and Their Association with Cervical Squamous Cell Carcinoma, and High- and Low-Grade Squamous Intraepithelial Lesions in Turkish Women.Iranian journal of public health · 2023Article
- Competing Endogenous RNA (ceRNA) Networks and Splicing Switches in Cervical Cancer: HPV Oncogenesis, Clinical Significance and Therapeutic Opportunities.Microorganisms · 2022Review
- Characterization of High-Risk HPV/EBV Co-Presence in Pre-Malignant Cervical Lesions and Squamous Cell Carcinomas.Microorganisms · 2022Article
- Determination of Human Papillomavirus Type 18 Lineage of E6: A Population Study from Iran.BioMed research international · 2022Article
- Maternal HPV Infection: Effects on Pregnancy Outcome.Viruses · 2021Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study investigated the distribution of HPV types in Korean women and evaluated the carcinogenic risk of individual HPV types and the potential effects of HPV vaccines. A total of 4,081 HPV-positive samples between 2014 and 2017 were included. The most prevalent genotypes were HPV 16, 58, 68, and 56. Among them, HPV 16 was significantly higher in high-grade squamous intraepithelial neoplasia or worse (HSIL+ ) group. In cytologically evaluating the risk for HSIL+ by individual HPV types, HPV 16 was associated with the highest risk of HSIL+ (OR = 10.82; 95% CI: 7.93-14.77), followed by HPV 33, 31, 52, 18, 58, 51, and 35, in descending order (OR = 3.50 [type 33] to 2.62 [type 35]). Among those types, HPV 16, 18, 31, 33, and 58 were also significantly associated with HSIL+ on histologic evaluation. The analysis of the HPV subgroups covered by the different vaccines revealed that the HPV types covered by the 9-valent vaccine had a high association with HSIL+ (OR = 4.09; 95% CI: 3.02-5.54). Our findings highlight the different carcinogenic risks posed by the high risk HPV genotypes and the positive potential effects of the 9-valent HPV vaccine in reducing HPV-associated cervical cancer in Korea.
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