ArticleScientific reports2019
Role of fundoplication in treatment of patients with symptoms of hiatal hernia.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- SAGES guidelines for the surgical treatment of hiatal hernias.Surgical endoscopy · 2024Guideline
- Management of symptomatic, asymptomatic, and recurrent hiatal hernia: a systematic review and meta-analysis.Surgical endoscopy · 2024Pooled it
- Evidence mapping on how to perform an optimal surgical repair of large hiatal hernias.Langenbeck's archives of surgery · 2023Pooled it
- Article
- Factors associated with postoperative symptom improvement and prediction model development in hiatal hernia patients: a retrospective study.BMC gastroenterology · 2026Article
- Current pharmacological and procedural treatments for gastro-oesophageal reflux disease: comprehensive review.BJS open · 2025Review
- No advantage of fundoplication in paraesophageal hernia repair: a retrospective multicenter study.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2025Article
- Current Trends in the Management of Hiatal Hernia: A Literature Review of 10 Years of Data.Cureus · 2024Review
- Clinical Outcome and Recurrence of Open versus Laparoscopic Nissen Fundoplication in the Republic of Kazakhstan during 2010-2021.Iranian journal of medical sciences · 2024Observational
- Paraesophageal hernia: to fundoplicate or not?Annals of translational medicine · 2021Review
- Laparoscopic repair of giant hiatal hernia for elderly patients.Annals of translational medicine · 2021Article
- Management of paraesophageal hernia review of clinical studies: timing to surgery, mesh use, fundoplication, gastropexy and other controversies.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2020Article
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8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastroesophageal reflux disease (GERD) is often associated with hiatal hernia (HH). However, the need for fundoplication during hiatal hernia repair (HHR) remains controversial. The objective of this study was to evaluate the effect of HHR with concomitant laparoscopic Nissen fundoplication (HHR-LNF) in HH patients. A total of 122 patients with symptomatic HH were randomized to receive either HHR (n = 61) or HHR-LNF (n = 61). The measures of evaluating outcomes included DeMeester scores (DMS), complications, Reflux Diagnostic Questionnaire and patients' satisfaction 24 months following surgery. Despite comparable values in both groups at randomization, the DMS, total numbers of reflux episodes and percentage of time with pH < 4 were significantly higher in HHR group than in HHR-LNF group (P = 0.017, P = 0.002 and P = 0.019, respectively) at 6 months after surgery. One months postoperatively, complications were higher in the HHR-LNF group than in the HHR group (all P < 0.001), and there was no difference between the two groups at 6 months. By the end of the 2-year follow-up, HHR-LNF group showed a significantly lower reflux syndrome frequency-intensity score and greater percentage of satisfaction compared with HHR group (all P < 0.001). Laparoscopic HHR should be combined with a fundoplication in GERD patients with HH. HHR-LNF is safe and effective, not only improve reflux-related symptom, but also reduce the incidence of complications.
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