Evidence map›Paper›PMID 31467195›Full record

ReviewScience (New York, N.Y.)2019

Cell migration and axon guidance at the border between central and peripheral nervous system.

Tracey A C S Suter, Alexander Jaworski

Abstract readReview
In one paragraph

Review in Science (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
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  5. Review
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  15. Synaptic promiscuity in brain development.Current biology : CB · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tracey A C S SuterDepartment of Neuroscience, Division of Biology and Medicine, Brown University, Providence, RI 02912, USA.ORCID 0000-0002-7091-2297
Alexander JaworskiDepartment of Neuroscience, Division of Biology and Medicine, Brown University, Providence, RI 02912, USA. alexander_jaworski@brown.edu.ORCID 0000-0002-4596-5450

Funding

Training CoreP20GM103430 · NIGMS · UNIVERSITY OF RHODE ISLAND · PI Bongsup P Cho · 2012 to 2026
$63.6M
Regulation of Nervous System Wiring by the Robo3 Axon Guidance Receptor and its Ligand NELL2R01NS095908 · NINDS · BROWN UNIVERSITY · PI JAWORSKI, ALEXANDER · 2017 to 2021
$2.2M
Predoctoral Training Program in Trans-Disciplinary Pharmacological SciencesT32GM077995 · NIGMS · BROWN UNIVERSITY · PI OANCEA, ELENA · 2010 to 2020
$1.7M
Understanding the Multifunctionality of TAG-1 in Motor Neuron DevelopmentF31NS098643 · NINDS · BROWN UNIVERSITY · PI SUTER, TRACEY AMELIA CLAIRE SAMPATH · 2016 to 2018
$128k
NIGMS NIH HHS P20 GM103430NIGMS NIH HHS T32 GM077995NINDS NIH HHS F31 NS098643NINDS NIH HHS R01 NS095908
6 · The paper itself

Abstract

The central and peripheral nervous system (CNS and PNS, respectively) are composed of distinct neuronal and glial cell types with specialized functional properties. However, a small number of select cells traverse the CNS-PNS boundary and connect these two major subdivisions of the nervous system. This pattern of segregation and selective connectivity is established during embryonic development, when neurons and glia migrate to their destinations and axons project to their targets. Here, we provide an overview of the cellular and molecular mechanisms that control cell migration and axon guidance at the vertebrate CNS-PNS border. We highlight recent advances on how cell bodies and axons are instructed to either cross or respect this boundary, and present open questions concerning the development and plasticity of the CNS-PNS interface.

Indexed as

Axon GuidanceCell MovementAnimalsAstrocytesBasement MembraneCentral Nervous SystemNeurogliaNeuronsPeripheral Nervous System

Identifiers

PMID31467195
PMCPMC6733266

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.