Evidence map›Paper›PMID 31467131›Full record

ReviewHaematologica2019

Guidelines from the 2017 European Conference on Infections in Leukaemia for management of HHV-6 infection in patients with hematologic malignancies and after hematopoietic stem cell transplantation.

Katherine N Ward, Joshua A Hill, Petr Hubacek, Rafael de la Camara, Roberto Crocchiolo, Hermann Einsele, David Navarro, Christine Robin, Catherine Cordonnier, Per Ljungman and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 3 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 3 syntheses or guidelines pooled it, 144 citations in OpenAlex.

  1. Guideline
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  17. Review
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  19. Uncovering the Cause of Pneumonia: Reactivation of HHV-6B in an Immunocompromised Patient.European journal of case reports in internal medicine · 2025
    Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 7 countries.

Katherine N WardDivision of Infection and Immunity, University College London, London, UK k.n.ward@ucl.ac.uk.
Joshua A HillFred Hutchinson Cancer Research Center, Seattle, WA, USA.
Petr HubacekDepartment of Medical Microbiology and Department of Paediatric Haematology and Oncology 2 Medical Faculty of Charles University and Motol University Hospital, Prague, Czech Republic.
Rafael de la CamaraDepartment of Haematology, Hospital de la Princesa, Madrid, Spain.
Roberto CrocchioloSIMT, ASST di Bergamo Ovest, Treviglio, Italy.
Hermann EinseleMedizinische Klinik und Poliklinik II, Julius Maximilians Universität, Würzburg, Germany.
David NavarroMicrobiology Service, Hospital Clínico Universitario, Instituto de Investigación INCLIVA and Department of Microbiology, School of Medicine, University of Valencia, Valencia, Spain.
Christine RobinDepartment of Haematology, Henri Mondor Hospital, Assistance Publique-Hopitaux de Paris, Université Paris-Est Créteil, Créteil, France.
Catherine CordonnierDepartment of Haematology, Henri Mondor Hospital, Assistance Publique-Hopitaux de Paris, Université Paris-Est Créteil, Créteil, France.
Per Ljungman
2017 European Conference on Infections in Leukaemia (ECIL)
Université Paris-Est Créteil · FRCharles University · CZFred Hutch Cancer Center · USHospital Universitario de La Princesa · ESKarolinska Institutet · SEUniversitat de València · ESUniversity College London · GBUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Of the two human herpesvirus 6 (HHV-6) species, human herpesvirus 6B (HHV-6B) encephalitis is an important cause of morbidity and mortality after allogeneic hematopoietic stem cell transplant. Guidelines for the management of HHV-6 infections in patients with hematologic malignancies or post-transplant were prepared a decade ago but there have been no other guidelines since then despite significant advances in the understanding of HHV-6 encephalitis, its therapy, and other aspects of HHV-6 disease in this patient population. Revised guidelines prepared at the 2017 European Conference on Infections in Leukaemia covering diagnosis, preventative strategies and management of HHV-6 disease are now presented.

Indexed as

Herpesvirus 6, HumanPractice Guidelines as TopicAntiviral AgentsCell Transformation, ViralCombined Modality TherapyEuropeGraft vs Host DiseaseHematologic NeoplasmsHematopoietic Stem Cell TransplantationHumansImmunocompromised HostRoseolovirus InfectionsTreatment OutcomeAntiviral Agents

Identifiers

PMID31467131
PMCPMC6821622
OpenAlexW2970999010

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.