Evidence map›Paper›PMID 31466553›Full record

ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2019

Low-cost, Small-scale Decontamination of Laboratory Equipment by Using Chlorine Dioxide Gas.

Cara M Mitchell, Alison McGrath, Breanne Beck, Michael J Schurr, Derek Fong, Jorik K Leszczynski, Christopher A Manuel

Abstract read
In one paragraph

Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cara M MitchellAnimal Resources Center, The University of Chicago Biological Sciences, Chicago, Illinois.
Alison McGrathDepartment of Environmental Health and Safety, Research Safety and Industrial Hygiene, Anschutz Medical Campus, University of Colorado-Denver.
Breanne BeckDepartment of Environmental Health and Safety, Research Safety and Industrial Hygiene, Anschutz Medical Campus, University of Colorado-Denver.
Michael J SchurrDepartment of Immunology and Microbiology, Research Safety and Industrial Hygiene, Anschutz Medical Campus, University of Colorado-Denver.
Derek FongOffice of Laboratory Animal Resources, Research Safety and Industrial Hygiene, Anschutz Medical Campus, University of Colorado-Denver; Department of Pathology, Research Safety and Industrial Hygiene, Anschutz Medical Campus, University of Colorado-Denver.
Jorik K LeszczynskiOffice of Laboratory Animal Resources, Research Safety and Industrial Hygiene, Anschutz Medical Campus, University of Colorado-Denver; Department of Pathology, Research Safety and Industrial Hygiene, Anschutz Medical Campus, University of Colorado-Denver.
Christopher A ManuelOffice of Laboratory Animal Resources, Research Safety and Industrial Hygiene, Anschutz Medical Campus, University of Colorado-Denver; Department of Pathology, Research Safety and Industrial Hygiene, Anschutz Medical Campus, University of Colorado-Denver; University of Colorado Cancer Center, Aurora, Colorado;, Email: Christopher.Manuel@ucdenver.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A significant concern in laboratory animal medicine is contamination due to pathogen outbreaks and how to adequately decontaminate small equipment. Many factors play a role in the selection of the decontamination method including cost, efficacy, personnel time and safety. Chlorine dioxide (ClO₂) gas is an effective method, but decontamination often requires a ClO₂ gas generator with a specialized air-tight exposure chamber. Although this method works well for large-scale decon- tamination, the use of a gas generator may be impractical and too costly for smaller-scale decontamination. The goal of this study was to create and validate an effective, small-scale decontamination method that uses ClO₂ gas and which is an affordable, efficient, safe, and reproducible. First, we identified a product that generates ClO₂ gas after the combination of 2 dry reagents. To find an affordable exposure chamber, we evaluated the ability of 4 household totes with gasket-seal lid systems to retain ClO₂ gas and relative humidity (RH). The efficacy of decontamination was validated by concurrently using 2 different biologic indicators (BI),

Indexed as

AnimalsChlorineChlorine CompoundsDecontaminationDisinfectantsEquipment ContaminationGasesOxidesChlorineChlorine Compoundschlorine dioxideDisinfectantsGasesOxides

Identifiers

PMID31466553
PMCPMC6774465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.