Evidence map›Paper›PMID 31466387›Full record

ArticleBiomolecules2019

Lignin and Cellulose Blends as Pharmaceutical Excipient for Tablet Manufacturing via Direct Compression.

Juan Domínguez-Robles, Sarah A Stewart, Andreas Rendl, Zoilo González, Ryan F Donnelly, Eneko Larrañeta

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 62 citations in OpenAlex.

  1. Polysaccharides and carbohydrate polymers: innovations from nature to industry.Journal of the science of food and agriculture · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Porphyrin Photosensitizers Grafted in Cellulose Supports: A Review.International journal of molecular sciences · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Juan Domínguez-RoblesSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Sarah A StewartSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Andreas RendlSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Zoilo GonzálezInstituto de Cerámica y Vidrio, CSIC, Calle Kelsen, 5, 28049 Madrid, Spain.
Ryan F DonnellySchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.
Eneko LarrañetaSchool of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK. e.larraneta@qub.ac.uk.
Queen's University Belfast · GBInstituto de Cerámica y Vidrio · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extensive efforts are being made to find alternative uses for lignin (LIG). In the present work the use of this biopolymer as excipient to prepare tablets was studied. For this purpose, LIG was combined with microcrystalline cellulose (MCC) and used as excipients to prepare directly compressed tablets containing a model drug, tetracycline (TC). The excipients contained different concentrations of LIG: 100%, 75%, 50%, 25% and 0% (

Indexed as

CelluloseChemistry, PharmaceuticalDrug CompoundingExcipientsLigninTabletsTetracyclineCelluloseExcipientsLigninmicrocrystalline celluloseTabletsTetracyclinedirect compressionligninmicrocrystalline cellulosepharmaceutical excipientstabletstetracycline

Identifiers

PMID31466387
PMCPMC6770814
OpenAlexW2971066352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.