Evidence map›Paper›PMID 31466337›Full record

ArticleMarine drugs2019

Antioxidant Fucoidans Obtained from Tropical Seaweed Protect Pre-Osteoblastic Cells from Hydrogen Peroxide-Induced Damage.

Gabriel Pereira Fidelis, Cynthia Haynara Ferreira Silva, Leonardo Thiago Duarte Barreto Nobre, Valquíria Pereira Medeiros, Hugo Alexandre Oliveira Rocha, Leandro Silva Costa

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Gabriel Pereira FidelisDepartment of Biochemistry, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte 59.078-970, Brazil.ORCID 0000-0003-1974-3771
Cynthia Haynara Ferreira SilvaDepartment of Biochemistry, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte 59.078-970, Brazil.
Leonardo Thiago Duarte Barreto NobreDepartment of Biochemistry, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte 59.078-970, Brazil.ORCID 0000-0002-4728-8035
Valquíria Pereira MedeirosDepartment of Biochemistry, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais 36036-900, Brazil.ORCID 0000-0002-9378-6481
Hugo Alexandre Oliveira RochaDepartment of Biochemistry, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte 59.078-970, Brazil. hugo@cb.ufrn.br.ORCID 0000-0003-2252-1221
Leandro Silva CostaInstituto Federal de Educação, Ciência, e Tecnologia do Rio Grande do Norte (IFRN), Rio Grande do Norte, Canguaretama, Rio Grande do Norte 59.500-000, Brazil.
Universidade Federal do Rio Grande do Norte · BRInstituto Federal do Rio Grande do Norte · BRUniversidade Federal de Juiz de Fora · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico Edital Universal, n° 408369/2016-7Coordenação de Aperfeiçoamento de Pessoal de Nível Superior AUXPE-CIMAR-1956/2014Coordenação de Aperfeiçoamento de Pessoal de Nível Superior CAPES/PROCAD n° 2965/2014
6 · The paper itself

Abstract

Some antioxidant compounds decrease the amount of intracellular reactive oxygen species (ROS) and consequently reduce the deleterious effects of ROS in osteoblasts. Thus, these compounds fight against osteoporosis. Brown seaweeds are a rich source of antioxidant fucose-containing sulfated polysaccharides (fucans and fucoidans). We obtained six fucoidans (FRFs)-F0.3, F0.5, F0.7, F1.0, F1.5, and F2.1-from

Indexed as

3T3 CellsAnimalsApoptosisCell DifferentiationFree Radical ScavengersHumansHydrogen PeroxideMiceOsteoblastsOsteoporosisOxidation-ReductionOxidative StressPhaeophyceaePolysaccharidesSeaweedFree Radical ScavengersfucoidanHydrogen PeroxidePolysaccharidesbone cellsbrown seaweedosteoporosisoxidative damagesulfated polysaccharides

Identifiers

PMID31466337
PMCPMC6780742
OpenAlexW2970284340

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.