Evidence map›Paper›PMID 31466318›Full record

ArticleMolecules (Basel, Switzerland)2019

Design, Synthesis, and Anticancer Effect Studies of Iridium(III) Polypyridyl Complexes against SGC-7901 Cells.

Li-Xia Zhang, Yi-Ying Gu, Yang-Jie Wang, Lan Bai, Fan Du, Wen-Yao Zhang, Miao He, Yun-Jun Liu, Yan-Zhong Chen

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Understanding the ancillary ligand effect on luminescent cyclometalated Ir(III) complex as a reporter for 2-acetylaminofluorene DNA(AAF-dG) adduct.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2022
    Article
  2. Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  3. Studies of anticancer activity in vivo and in vitro behaviors of liposomes encapsulated iridium(III) complex.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Li-Xia ZhangGuangdong Provincial Key Laboratory of Advanced Drug Delivery Systems, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Yi-Ying GuSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Yang-Jie WangSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Lan BaiSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Fan DuSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Wen-Yao ZhangSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Miao HeSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Yun-Jun LiuSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China. lyjche@gdpu.edu.cn.ORCID 0000-0001-5396-9147
Yan-Zhong ChenGuangdong Provincial Key Laboratory of Advanced Drug Delivery Systems, Guangdong Pharmaceutical University, Guangzhou 510006, China. chenyanzhong@gdpu.edu.cn.
Guangdong Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three iridium(III) complexes ([Ir(Hppy)

Indexed as

A549 CellsAnimalsCell Line, TumorCell ProliferationCell SurvivalCoordination ComplexesDrug DesignDrug Screening Assays, AntitumorHeLa CellsHep G2 CellsHumansInhibitory Concentration 50IridiumMiceNIH 3T3 CellsPyridinesCoordination ComplexesIridiumPyridinesReactive Oxygen Speciesantitumor activityapoptosisDNA damageiridium(III) complexesmitochondrial dysfunction

Identifiers

PMID31466318
PMCPMC6749586
OpenAlexW2970517667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.