Evidence map›Paper›PMID 31466283›Full record

ArticleGenes2019

Affinity Purification of NF1 Protein-Protein Interactors Identifies Keratins and Neurofibromin Itself as Binding Partners.

Rachel M Carnes, Robert A Kesterson, Bruce R Korf, James A Mobley, Deeann Wallis

Open access · goldAbstract read
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Repair of MutatedCancers · 2025
    Article
  3. Article
  4. Review
  5. Tagging Recombinant Proteins to Enhance Solubility and Aid Purification.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Mutation-Directed Therapeutics for Neurofibromatosis Type I.Molecular therapy. Nucleic acids · 2020
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rachel M CarnesDepartment of Genetics, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Robert A KestersonDepartment of Genetics, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0003-1331-0780
Bruce R KorfDepartment of Genetics, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
James A MobleyDepartment of Anesthesiology and Perioperative Medicine, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Deeann WallisDepartment of Genetics, The University of Alabama at Birmingham, Birmingham, AL 35294, USA. dwallis@uab.edu.ORCID 0000-0002-8217-0892
University of Alabama at Birmingham · US

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
NCI NIH HHS P30 CA013148
6 · The paper itself

Abstract

Neurofibromatosis Type 1 (NF1) is caused by pathogenic variants in the

Indexed as

HEK293 CellsHumansKeratinsNeurofibromin 1Protein BindingProtein MultimerizationKeratinsNeurofibromin 1NF1 protein, humanaffinity purificationbinding partnersimmunoprecipitationkeratinsmass spectrometryneurofibromatosis Type Ineurofibrominprotein–protein interactorsRas

Identifiers

PMID31466283
PMCPMC6770187
OpenAlexW2970362619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.