Evidence map›Paper›PMID 31466275›Full record

ArticleMaterials (Basel, Switzerland)2019

High Bactericidal Self-Assembled Nano-Monolayer of Silver Sulfadiazine on Hydroxylated Material Surfaces.

Angelo Taglietti, Giacomo Dacarro, Daniele Barbieri, Lucia Cucca, Pietro Grisoli, Maddalena Patrini, Carla Renata Arciola, Piersandro Pallavicini

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Multifunctional TPU-HAp/HA-TiOInternational journal of pharmaceutics: X · 2026
    Article
  2. Article
  3. A Supramolecular Approach to Antimicrobial Surfaces.Molecules (Basel, Switzerland) · 2022
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Angelo TagliettiDipartimento di Chimica, Sezione di Chimica Generale, Università di Pavia, viale Taramelli 12, 27100 Pavia, Italy. angelo.taglietti@unipv.it.ORCID 0000-0003-0141-9201
Giacomo DacarroDipartimento di Chimica, Sezione di Chimica Generale, Università di Pavia, viale Taramelli 12, 27100 Pavia, Italy. giacomo.dacarro@unipv.it.ORCID 0000-0002-8928-4972
Daniele BarbieriDipartimento di Chimica, Sezione di Chimica Generale, Università di Pavia, viale Taramelli 12, 27100 Pavia, Italy.
Lucia CuccaDipartimento di Chimica, Sezione di Chimica Generale, Università di Pavia, viale Taramelli 12, 27100 Pavia, Italy.
Pietro GrisoliDipartimento di Scienze del Farmaco, Università di Pavia, viale Taramelli 10, 27100 Pavia, Italy.
Maddalena PatriniDipartimento di Fisica, "A. Volta", Università di Pavia, via Bassi 6, 27100 Pavia, Italy.
Carla Renata ArciolaLaboratorio di Patologia delle Infezioni Associate all'Impianto, IRCCS Istituto Ortopedico Rizzoli, via di Barbiano 1/10, 40136 Bologna, Italy. carlarenata.arciola@ior.it.ORCID 0000-0003-0382-0066
Piersandro PallaviciniDipartimento di Chimica, Sezione di Chimica Generale, Università di Pavia, viale Taramelli 12, 27100 Pavia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-infective surfaces are a modern strategy to address the issue of infection related to the clinical use of materials for implants and medical devices. Nanocoatings, with their high surface/mass ratio, lend themselves to being mono-layered on the material surfaces to release antibacterial molecules and prevent bacterial adhesion. Here, a "layer-by-layer" (LbL) approach to achieve a self-assembled monolayer (SAM) with high microbicidal effect on hydroxylated surfaces is presented, exploiting the reaction between a monolayer of thiolic functions on glass/quartz surfaces and a newly synthesized derivative of the well-known antibacterial compound silver sulfadiazine. Using several different techniques, it is demonstrated that a nano-monolayer of silver sulfadiazine is formed on the surfaces. The surface-functionalized materials showed efficient bactericidal effect against both Gram-positive and Gram-negative bacteria. Interestingly, bactericidal self-assembled nano-monolayers of silver sulfadiazine could be achieved on a large variety of materials by simply pre-depositing glass-like SiO

Indexed as

anti-infective materialsantimicrobialnanocoatingsself-assembled monolayersulfadiazine

Identifiers

PMID31466275
PMCPMC6748069

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.