ReviewMedicina (Kaunas, Lithuania)2019
Vitamin D Deficiency: Consequence or Cause of Obesity?
Review in Medicina (Kaunas, Lithuania), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 179 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
179 citing papers in PubMed, 7 syntheses or guidelines pooled it, 308 citations in OpenAlex.
- Can Vitamin D supplementation enhance the effectiveness of exercise-induced weight loss in overweight or obese adults? Evidence from integrated transcriptomic and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Racial disparities in selected micronutrient deficiencies after bariatric surgery: A systematic review.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2024Pooled it
- Obstructive sleep apnea and vitamin D: an updated systematic review and meta-analysis.Hormones (Athens, Greece) · 2023Pooled it
- A Systematic Review and Meta-Analysis of Vitamin D Status of Patients with Severe Obesity in Various Regions Worldwide.Obesity facts · 2023Pooled it
- Vitamin D supplementation positively affects anthropometric indices: Evidence obtained from an umbrella meta-analysis.Frontiers in nutrition · 2022Pooled it
- The role of vitamin D in the age of COVID-19: A systematic review and meta-analysis.International journal of clinical practice · 2021Pooled it
- A systematic review and meta-analysis of effect of vitamin D levels on the incidence of COVID-19.Cardiology journal · 2021Pooled it
- Effect of age and body mass index on vitamin D level in children with asthma in Riyadh.Scientific reports · 2021Trial
- No Difference in Weight Loss, Glucose, Lipids and Vitamin D of Eggs for Breakfast Compared with Cereal for Breakfast during Energy Restriction.International journal of environmental research and public health · 2020Trial
- Efficiency of Vitamin D Supplementation in Healthy Adults is Associated with Body Mass Index and Baseline Serum 25-Hydroxyvitamin D Level.Nutrients · 2020Trial
- Article
- Vitamin D₃ in cancer prevention and therapy: molecular mechanisms, clinical evidence, and future perspectives.Molecular biology reports · 2026Review
- Vitamin D and adverse pathologic features in patients undergoing radical prostatectomy in the contemporary magnetic resonance imaging-guided management era.BJUI compass · 2026Article
- Impact of Vitamin D Supplementation on Hospitalizations for Infection: Results of the D-Health Trial Revisited.Nutrients · 2026Article
- Evaluating Outcomes in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease and Vitamin D Deficiency.Diseases (Basel, Switzerland) · 2026Article
- Prevalence and determinants of secondary hyperparathyroidism: IMOS-2021.Scientific reports · 2026Article
- Article
- Comparison of vitamin D, parathyroid hormone, and body composition in obese premenopausal and postmenopausal women.Endocrine · 2026Article
- Vitamin D and Disease Perception Outcomes in a Cluster of Patients with High-Disease-Activity Chronic Spontaneous Urticaria.Journal of clinical medicine · 2026Article
- Vitamin D deficiency and depression in obese adults: NHANES 2009-2018.Irish journal of medical science · 2026Article
119 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is defined as an excess amount of body fat and represents a significant health problem worldwide. High prevalence of vitamin D (VD) deficiency in obese subjects is a well-documented finding, most probably due to volumetric dilution into the greater volumes of fat, serum, liver, and muscle, even though other mechanisms could not completely be excluded, as they may contribute concurrently. Low VD could not yet be excluded as a cause of obesity, due to its still incompletely explored effects through VD receptors found in adipose tissue (AT). VD deficiency in obese people does not seem to have consequences for bone tissue, but may affect other organs, even though studies have shown inconsistent results and VD supplementation has not yet been clearly shown to benefit the dysmetabolic state. Hence, more studies are needed to determine the actual role of VD deficiency in development of those disorders. Thus, targeting lifestyle through healthy diet and exercise should be the first treatment option that will affect both obesity-related dysmetabolic state and vitamin D deficiency, killing two birds with one stone. However, VD supplementation remains a treatment option in individuals with residual VD deficiency after weight loss.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.