Evidence map›Paper›PMID 31466075›Full record

ReviewNeuroendocrinology2020

Differential Roles of Hypothalamic AVPV and Arcuate Kisspeptin Neurons in Estradiol Feedback Regulation of Female Reproduction.

Luhong Wang, Suzanne M Moenter

Open access · greenAbstract readReview
In one paragraph

Review in Neuroendocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Role of circadian clock in female embryo implantation.Frontiers in cell and developmental biology · 2025
    Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Hypothalamic Kisspeptin Neurons: Integral Elements of the GnRH System.Reproductive sciences (Thousand Oaks, Calif.) · 2023
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Luhong WangDepartment of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, USA.
Suzanne M MoenterDepartment of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, USA, smoenter@umich.edu.
University of Michigan–Ann Arbor · US

Funding

Central Actions of Estrogens: Effects on GnRH NeuronsR01HD041469 · NICHD · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Suzanne M MOENTER · 2002 to 2026
$8.8M
NICHD NIH HHS R01 HD041469
6 · The paper itself

Abstract

Mammalian reproductive function includes puberty onset and completion, reproductive cyclicity, steroidogenesis, gametogenesis, fertilization, pregnancy, and lactation; all are indispensable to perpetuate species. Reproductive cycles are critical for providing the hormonal milieu needed for follicular development and maturation of eggs, but cycles, in and of themselves, do not guarantee ovulation will occur. Here, we review the roles in female reproductive neuroendocrine function of two hypothalamic populations that produce the neuropeptide kisspeptin, demonstrating distinct roles in maintaining cycles and ovulation.

Indexed as

ReproductionAnimalsArcuate Nucleus of HypothalamusEstradiolFemaleHumansHypothalamus, AnteriorKisspeptinsOvulationEstradiolKisspeptinsAnteroventral periventricular nucleusArcuateCRISPREstradiolKisspeptinOvulationReproduction

Identifiers

PMID31466075
PMCPMC7047625
OpenAlexW2976798017

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.