Evidence map›Paper›PMID 31465832›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2020

Computerized Adaptive Tests for Rapid and Accurate Assessment of Psychopathology Dimensions in Youth.

Robert D Gibbons, David J Kupfer, Ellen Frank, Benjamin B Lahey, Brandie A George-Milford, Candice L Biernesser, Giovanna Porta, Tara L Moore, Jong Bae Kim, David A Brent

2 registry-linked trialsAbstract read
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07401940 narecruitingnot on this mapstarted 2023, after this paper: background citation

A Multi-Generational Suicide Prevention Program in African American Churches

TypeinterventionalSponsorGeorge Washington UniversityRan2023 to 2026Enrolled240ConditionsSuicide PreventionArmsHAVEN-Connect, HAVEN Suicide Prevention
NCT07664631 phase1not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effects of Stimulant Medications in PTSD

TypeinterventionalSponsorUniversity of ChicagoRan2026 to 2027Enrolled40ConditionsAdderall, PTSD, Post Traumatic Stress DisorderArmsPlacebo, Adderall
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  20. Community Teens' COVID-19 Experience: Implications for Engagement Moving Forward.Journal of clinical psychology in medical settings · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Robert D GibbonsUniversity of Chicago, Illinois. Electronic address: rdg@uchicago.edu.
David J KupferUniversity of Pittsburgh School of Medicine, Pennsylvania.
Ellen FrankUniversity of Pittsburgh School of Medicine, Pennsylvania.
Benjamin B LaheyUniversity of Chicago, Illinois.
Brandie A George-MilfordUPMC Western Psychiatric Hospital, Pittsburgh, Pennsylvania.
Candice L BiernesserUPMC Western Psychiatric Hospital and the University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania.
Giovanna PortaUPMC Western Psychiatric Hospital, Pittsburgh, Pennsylvania.
Tara L MooreHealthRhythms, Inc., New York.
Jong Bae KimCenter for Health Statistics, University of Chicago, Illinois.
David A BrentUniversity of Pittsburgh School of Medicine, Pennsylvania; UPMC Western Psychiatric Hospital, Pittsburgh, Pennsylvania.

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
Harnessing Computerized Adaptive Testing, Transdiagnostic Theories of Suicidal Behavior, and Machine Learning to Advance the Emergent Assessment of Suicidal Youth (EASY).R01MH100155 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BRENT, DAVID A., GIBBONS, ROBERT D · 2013 to 2022
$8.0M
NCATS NIH HHS UL1 TR001857NIMH NIH HHS R01 MH100155
6 · The paper itself

Abstract

objectiveAt least half of youths with mental disorders are unrecognized and untreated. Rapid, accurate assessment of child mental disorders could facilitate identification and referral and potentially reduce the occurrence of functional disability that stems from early-onset mental disorders.

methodComputerized adaptive tests (CATs) based on multidimensional item response theory were developed for depression, anxiety, mania/hypomania, attention-deficit/hyperactivity disorder, conduct disorder, oppositional defiant disorder, and suicidality, based on parent and child ratings of 1,060 items each. In phase 1, CATs were developed from 801 participants. In phase 2, predictive, discriminant, and convergent validity were tested against semi-structured research interviews for diagnoses and suicidality in 497 patients and 104 healthy controls. Overall strength of association was determined by area under the receiver operating characteristic curve (AUC).

resultsThe child and parent independently completed the Kiddie-Computerized Adaptive Tests (K-CATs) in a median time of 7.56 and 5.03 minutes, respectively, with an average of 7 items per domain. The K-CATs accurately captured the presence of diagnoses (AUCs from 0.83 for generalized anxiety disorder to 0.92 for major depressive disorder) and suicidal ideation (AUC = 0.996). Strong correlations with extant measures were found (r ≥ 0.60). Test-retest reliability averaged r = 0.80.

conclusionThese K-CATs provide a new approach to child psychopathology screening and measurement. Testing can be completed by child and parent in less than 8 minutes and yields results that are highly convergent with much more time-consuming structured clinical interviews and dimensional severity assessment and measurement. Testing of the implementation of the K-CAT is now indicated.

Indexed as

Major Depressive DisorderAdolescentAnxietyAnxiety DisordersHumansPsychopathologyReproducibility of Resultsadaptive testingchild and adolescent psychopathologydiagnosismeasurementmultidimensional item response theory

Identifiers

PMID31465832
PMCPMC7042076

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.