Evidence map›Paper›PMID 31465773›Full record

ArticleBrain research2019

Differences between normal and diabetic brains in middle-aged rats by MRI.

Guangliang Ding, Michael Chopp, Lian Li, Li Zhang, Esmaeil Davoodi-Bojd, Qingjiang Li, Min Wei, Zhenggang Zhang, Quan Jiang

Open access · greenAbstract read
In one paragraph

Article in Brain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Guangliang DingDepartment of Neurology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA.
Michael ChoppDepartment of Neurology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA; Department of Physics, Oakland University, Rochester, MI 48309, USA.
Lian LiDepartment of Neurology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA.
Li ZhangDepartment of Neurology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA.
Esmaeil Davoodi-BojdDepartment of Neurology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA.
Qingjiang LiDepartment of Neurology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA.
Min WeiDepartment of Neurology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA.
Zhenggang ZhangDepartment of Neurology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA.
Quan JiangDepartment of Neurology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA; Department of Physics, Oakland University, Rochester, MI 48309, USA. Electronic address: qjiang1@hfhs.org.
Henry Ford Hospital · USOakland University · US

Funding

Interaction between glymphatic and vascular systems for waste clearance in brain - Administrative SupplementR01NS108463 · NINDS · HENRY FORD HEALTH SYSTEM · PI HU, JIANI, JIANG, QUAN · 2018 to 2022
$3.1M
Glymphatic and cognitive impairment of aging and diabetesRF1AG057494 · NIA · HENRY FORD HEALTH SYSTEM · PI JIANG, QUAN, ZHANG, LI · 2017 to 2017
$2.9M
Exosomes and platinum-induced peripheral neuropathyR01CA219829 · NCI · HENRY FORD HEALTH SYSTEM · PI ZHANG, ZHENG GANG · 2018 to 2022
$1.8M
Ac-SDKP for Treatment of Acute StrokeR01NS079612 · NINDS · HENRY FORD HEALTH SYSTEM · PI ZHANG, ZHENG GANG · 2013 to 2017
$1.6M
Imaging Cell Based Treatment of Traumatic Brain InjuryR01NS064134 · NINDS · HENRY FORD HEALTH SYSTEM · PI JIANG, QUAN · 2011 to 2014
$1.3M
Impairment of the glymphatic system in the aged diabetic brainR21AG052735 · NIA · HENRY FORD HEALTH SYSTEM · PI JIANG, QUAN, ZHANG, LI · 2016 to 2017
$412k
NCI NIH HHS R01 CA219829NIA NIH HHS R21 AG052735NIA NIH HHS RF1 AG057494NINDS NIH HHS R01 NS064134NINDS NIH HHS R01 NS079612NINDS NIH HHS R01 NS108463
6 · The paper itself

Abstract

Normal aging is a risk factor for metabolic disorders such as diabetes, and diabetes is also a recognized cause of accelerated aging. Being able to distinguish changes caused by normal aging from those caused by diabetes, would provide insight into how the aging brain interacts with diabetes. Eight types of MRI metric maps (magnetization relaxation time constants of T

Indexed as

Age FactorsAgingAnimalsAnisotropyBrainDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2Diffusion Magnetic Resonance ImagingDiffusion Tensor ImagingDisease Models, AnimalGray MatterMagnetic Resonance ImagingMaleRatsRats, WistarStreptozocinStreptozocinAgingDiabetesGray matterMagnetic resonance imagingRatWhite matter

Identifiers

PMID31465773
PMCPMC8063608
OpenAlexW2970332790

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.