Evidence map›Paper›PMID 31465429›Full record

ArticlePloS one2019

Characterization of difference in structure and function of fresh and mastitic bovine milk fat globules.

Aparna Verma, Tamoghna Ghosh, Bharat Bhushan, Gopinath Packirisamy, Naveen K Navani, Pranita P Sarangi, Kiran Ambatipudi

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  6. Shiga Toxin-ProducingMicroorganisms · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Aparna VermaDepartment of Biotechnology, Indian Institute of Technology, Roorkee, India.
Tamoghna GhoshDepartment of Biotechnology, Indian Institute of Technology, Roorkee, India.
Bharat BhushanCenter for Nanotechnology, Indian Institute of Technology, Roorkee, India.
Gopinath PackirisamyDepartment of Biotechnology, Indian Institute of Technology, Roorkee, India.
Naveen K NavaniDepartment of Biotechnology, Indian Institute of Technology, Roorkee, India.
Pranita P SarangiDepartment of Biotechnology, Indian Institute of Technology, Roorkee, India.
Kiran AmbatipudiDepartment of Biotechnology, Indian Institute of Technology, Roorkee, India.ORCID 0000-0001-7611-3579
Indian Institute of Technology Roorkee · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Characterization of milk fat globule (MFG) was performed to investigate the difference in MFG membrane (MFGM) between fresh and mastitis Holstein Friesian cow milk. Lipid distribution investigated by exogenous phospholipids using microscopy showed higher phospholipid content in fresh compared to mastitic MFGM. Xanthine oxidase assay indicative of membrane impairment revealed lower activity in mastitic samples compared to fresh globules. Of note, significantly higher roughness of globule surface and zeta potential was observed in mastitis compared to fresh globules. Influence of globule membrane on the interaction with L. fermentum demonstrated preferential adhesion of bacteria to fresh compared to mastitic globules including enhanced extent of binding. Results of the present study provides an insight of the interfacial changes occurring at the globule surface as well as highlighting the importance of selective bacterial interaction with milk components for the potential development of functional food with relevance to human health.

Indexed as

AnimalsCattleFemaleFlow CytometryFood AnalysisGlycolipidsGlycoproteinsLipid DropletsMastitis, BovineMicroscopy, Atomic ForcePhospholipidsStructure-Activity RelationshipXanthine OxidaseGlycolipidsGlycoproteinsmilk fat globulePhospholipidsXanthine Oxidase

Identifiers

PMID31465429
PMCPMC6715232
OpenAlexW2970832558

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.