Evidence map›Paper›PMID 31465285›Full record

ReviewCurrent pediatric reviews2019

Is Pouch Specific to Colon and Not Ileum?

Sonal Gupta, Pradeep Tiwari, Nidhi Gupta, Vandana Nunia, Amulya K Saxena, Anita Simlot, Shanker Lal Kothari, Prashanth Suravajhala, Krishna Mohan Medicherla, Praveen Mathur

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current pediatric reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Sonal GuptaDepartment of Biotechnology and Bioinformatics, Birla Institute of Scientific Research, Jaipur 302001, RJ, India.
Pradeep TiwariDepartment of Chemistry, School of Basic Sciences, Manipal University Jaipur, Jaipur 303007, RJ, India.
Nidhi GuptaDepartment of Biotechnology, IIS (Deemed to be University), Mansarovar, Jaipur 302020, India.
Vandana NuniaDepartment of Zoology, University of Rajasthan, Jaipur 302004, RJ, India.
Amulya K SaxenaDepartment of Pediatric Surgery, Imperial College London, United Kingdom.
Anita SimlotDepartment of Obstretrics and Gynaecology, SMS Medical College, JLN Marg, Jaipur 302004 RJ, India.
Shanker Lal KothariDepartment of Biotechnology, Amity University Rajasthan, Jaipur 303002 RJ, India.
Prashanth SuravajhalaDepartment of Biotechnology and Bioinformatics, Birla Institute of Scientific Research, Jaipur 302001, RJ, India.
Krishna Mohan MedicherlaDepartment of Biotechnology and Bioinformatics, Birla Institute of Scientific Research, Jaipur 302001, RJ, India.
Praveen MathurDepartment of Pediatric Surgery, SMS Medical College, JLN Marg, Jaipur 302004 RJ, India.
Birla Institute of Scientific Research · INSMS Medical College · INImperial College London · GBManipal University JaipurUniversity of Rajasthan · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCongenital Pouch Colon (CPC) is an anorectal anomaly with an incidence of 3.5:1 in males and females, respectively. We have earlier reported CPC to be quite prevalent in north Indian tertiary care centers.

objectiveIn this article, we deliberate on the possible causes associated with CPC bringing the manifestation of the disease. In addition, we throw insights on the effective role of this congenital anomaly in Colon and provide systems genomic evaluation by comparing our recent analysis to that of Colon and Ileum based on Next-Generation Sequencing (NGS) studies.

conclusionIn this commentary article, we argue that a host of epigenetic factors could be the reason why the disease is manifested in colon alone. We further hypothesize on the few unmet challenges linking epigenetics to understand the genetic variants.

Indexed as

Anorectal MalformationsChildColonDigestive System Surgical ProceduresExome SequencingFecal IncontinenceHigh-Throughput Nucleotide SequencingHumansIleumPostoperative Complicationsanorectal malformationcolostomycolovesical fistulaCongenital pouch colonimperforate anussystems genomics.

Identifiers

PMID31465285
PMCPMC7040526
OpenAlexW2970771693

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.