Evidence map›Paper›PMID 31464941›Full record

Observational studyMedicine2019

HPV testing on vaginal/cervical nurse-assisted self-samples versus clinician-taken specimens and the HPV prevalence, in Adama Town, Ethiopia.

Eshetu Lemma Haile, Simoens Cindy, Benoy Ina, Gurja Belay, Van Geertruyden Jean-Pierre, Ransom Sharon, Lebelo Ramokone Lisbeth, Bogers Johannes Paul

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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  14. Cervical human papillomavirus DNA detection in women living with HIV and HIV-uninfected women living in Limbe, Cameroon.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Eshetu Lemma HaileUniversity of Antwerp, Antwerpen, Belgium.
Simoens CindyUniversity of Antwerp, Antwerpen, Belgium.
Benoy InaUniversity of Antwerp, Antwerpen, Belgium.
Gurja BelayAddis Ababa University, Addis Ababa, Ethiopia.
Van Geertruyden Jean-PierreUniversity of Antwerp, Antwerpen, Belgium.
Ransom SharonInternational Partnership for Reproductive Health, Bryan, OH.
Lebelo Ramokone LisbethSefako Makgatho Health Sciences University (SMU), Gauteng Province, South Africa.
Bogers Johannes PaulUniversity of Antwerp, Antwerpen, Belgium.
University of Antwerp · BEAddis Ababa University · ETInstitute for Reproductive Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to determine the feasibility of vaginal/cervical nurse-assisted self-sampling (NASS) and the agreement between human papilloma virus (HPV) tests on self-samples versus clinician-taken (CT) specimens.Women participated voluntarily for cervical cancer screening at St. Aklesia Memorial Hospital. Eighty-three women provided a total of 166 coupled self-taken and CT specimens collected. Specimens were stored at room temperature for a maximum of 10 months and analyzed using validated the RIATOL qPCR HPV genotyping test, a quantitative polymerase chain reaction (qPCR) high-throughput HPV E6, E7 assay. The average age of the participating women was 32 years. Seventy-three women (87.9%) felt that NASS was easy to use. An overall HPV, high-risk (HR) HPV, and low-risk HPV prevalence was 22.7% (15/66), 18.2% (12/66), and 6.1% (4/66), respectively. The overall HR HPV prevalence was 17.2% (NASS) and 15.5% (CT). The most prevalent HPV type was HPV51; HPV 16 was only detected in 1 woman (CT+NASS) and HPV18 only in 1 woman (CT). The overall measurement agreement between self-taken and CT samples was moderate with a kappa value of 0.576 (P < .001). Lifetime partnered with >2 men were associated with HR HPV positivity (P < .001). There was a strong statistical association between HR HPV positivity and visual inspection with acetic acid- positive (P < .001). The NASS for HPV testing could be seen as an alternative option and might be acceptable to Ethiopian women. The overall HR HPV prevalence was comparable with Sub-Saharan countries in the general population.

Indexed as

AdultAgedEarly Detection of CancerEthiopiaFemaleGenotypeHumansMiddle AgedPapillomavirus InfectionsReal-Time Polymerase Chain ReactionSensitivity and SpecificitySpecimen HandlingUterine Cervical NeoplasmsVaginal SmearsYoung Adult

Identifiers

PMID31464941
PMCPMC6736428
OpenAlexW2970480891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.