Evidence map›Paper›PMID 31464914›Full record

ArticleMedicine2019

Clinical outcomes of endoscopic balloon dilatation of intestinal strictures in patients with Crohn's disease.

Ophir Winder, Naomi Fliss-Isakov, Gilad Winder, Erez Scapa, Henit Yanai, Sophie Barnes, Roy Dekel, Iris Dotan, Nitsan Maharshak

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ophir WinderDepartment of Gastroenterology and Liver Diseases.
Naomi Fliss-IsakovDepartment of Gastroenterology and Liver Diseases.
Gilad WinderDepartment of Gastroenterology and Liver Diseases.
Erez ScapaDepartment of Gastroenterology and Liver Diseases.
Henit YanaiSackler Faculty of Medicine, Tel Aviv University.
Sophie BarnesSackler Faculty of Medicine, Tel Aviv University.
Roy DekelSackler Faculty of Medicine, Tel Aviv University.
Iris DotanSackler Faculty of Medicine, Tel Aviv University.
Nitsan MaharshakDepartment of Gastroenterology and Liver Diseases.
Tel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal strictures are common complications of Crohn's disease (CD). Endoscopic balloon dilatation (EBD) constitutes an alternative therapy to surgery, but associated factors of procedure success are inconclusive. Therefore, we aimed to evaluate the EBD success rate and its associated factors in CD patients.This is a retrospective cohort study of consecutive EBDs that were conducted between 2006 and 2014 among patients with CD with lower gastrointestinal tract strictures. Patients' and stricture characteristics, short term procedure success and related complications at 1 week follow-up, and long-term clinical endpoints were documented.A total of 138 dilatations were performed on 64 CD patients. The overall dilatation success rate was 84.8%, with no difference between primary or anastomotic strictures, or between first or recurrent dilatation procedures. Long strictures (≥4 cm) were negatively associated with successful EBDs, but not with perforations. A multivariate analysis adjusting for age, sex, smoking, and disease duration revealed that a maximal dilatation diameter of ≥15 mm was positively associated with a successful EBD, while an inflamed stricture was negatively associated with procedure success. Strictures which were both long and inflamed were associated with the lowest EBD success rates compared with other strictures. Only 32.8% of patients required surgery during the follow-up period. Long-term prevention of surgery was negatively associated with stricture length and with a successful EBD.EBD is highly successful in treating intestinal strictures and in prevention of surgery in CD patients. Although EBD of long strictures is safe, it will not prevent surgery in the majority of cases.

Indexed as

AdultAgedBalloon EnteroscopyConstriction, PathologicCrohn DiseaseDilatationFemaleHumansIntestinal ObstructionIsraelMaleMiddle AgedMultivariate AnalysisRetrospective StudiesTertiary Care Centers

Identifiers

PMID31464914
PMCPMC6736228
OpenAlexW2970125670

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.