Observational studyMedicine2019
Endoscopic findings and outcome in caustic ingestion of acidic and alkaline agents in adults: A retrospective analysis.
Observational study in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Short-term and long-term management of caustic-induced gastrointestinal injury: An evidence-based practice guidelines.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025Guideline
- Surgical reconstruction of caustic esophageal strictures: a retrospective comparative study of esophagogastroplasty and esophagocoloplasty.BMC surgery · 2025Article
- Esophageal Mucosal Injuries From Drugs, Radiation, and Caustic Agents.The Korean journal of helicobacter and upper gastrointestinal research · 2025Review
- Long-term outcomes of patients undergoing emergency surgery for corrosive injury of the upper digestive tract.Surgery today · 2025Article
- The Effects of Ellagic Acid on Experimental Corrosive Esophageal Burn Injury.Current issues in molecular biology · 2024Article
- Ingestion of corrosive substances and the endoscopic role in assessing the severity of caustic injury.Przeglad gastroenterologiczny · 2023Article
- Foreign body ingestion: Is intervention always a necessity?Annals of medicine and surgery (2012) · 2022Article
- Developing the minimum data set of the corrosive ingestion registry system in Iran.BMC health services research · 2022Review
- Article
- Endoscopic, laboratory, and clinical findings and outcomes of caustic ingestion in adults; a retrospective study.Gastroenterology and hepatology from bed to bench · 2022Article
- Esophageal Stricture Caused by the Ingestion of Undissolved Picosulfate Powder.Clinical endoscopy · 2021Article
- Two rare case reports of ingestion of ammonium hydroxide and novel study of gastrointestinal toxicity.BMJ open gastroenterology · 2019Article
- Adult Caustic Ingestion with Surprisingly Benign Outcomes: A Need for Careful Interpretation of Endoscopic Findings.GE Portuguese journal of gastroenterologyArticle
- Adult Caustic Ingestion with Surprisingly Benign Outcomes: A Need for Careful Interpretation of Endoscopic Findings.GE Portuguese journal of gastroenterologyArticle
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Caustic ingestion in adults is a rare but potentially life-threatening problem. It remains controversial whether endoscopic findings and mortality differ between acid and alkali ingestion. We compared ingestion of these agents and evaluated prediction parameters for survival and complications.Adult patients who presented with caustic ingestion were analyzed from 2005 to 2016. Mucosal injury was graded endoscopically by Zargar's score. Age, gender, intent of ingestion, caustic agents, comorbidities, management, complications, and mortality were examined.Thirty-one patients met inclusion criteria and were divided into acid (n = 10) and alkali group (n = 21). Ingestion of alkali resulted in higher grades (≥III) of esophageal (56% vs 24%, P = .01) and stomach injuries (43% vs 13%, P = .05) and was mostly done with suicidal intent (76% vs 30%, P = .003). Patients in the alkali group received more often surgical interventions, mechanical ventilation and tracheotomy. Overall complications including Zargar's-score ≥ grade III, mediastinitis, and aspiration pneumonia were higher in alkali group but all showed no statistical significance (P = .73). Mortality (acid: 1 (10%), alkali: 4 (19%), P = .52), age, gender, comorbidities, and intensive care management did not differ significantly between the groups. Chronic renal failure and mediastinitis were promising prediction parameters for mortality but did not reach statistical significance. No independent risk factors for the development of esophageal stenosis were identified.Alkaline agents caused a higher mucosal injury severity and were more often used in suicidal intent. Mediastinitis and chronic renal failure might be potential prediction parameters for survival but need to be evaluated in larger studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.