ArticleMolecular systems biology2019
Inaccuracy of the log-rank approximation in cancer data analysis.
Article in Molecular systems biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Biomarker discovery and patient stratification in pancreatic cancer using incomplete multi-omics data.PLoS computational biology · 2026Article
- The Proteogenomics of Prostate Cancer Radioresistance.Cancer research communications · 2024Article
- Integration of gene expression and DNA methylation data across different experiments.Nucleic acids research · 2023Article
- Detecting molecular subtypes from multi-omics datasets using SUMO.Cell reports methods · 2022Article
- Consensus clustering applied to multi-omics disease subtyping.BMC bioinformatics · 2021Article
- Enhancer-derived long non-coding RNAs CCAT1 and CCAT2 at rs6983267 has limited predictability for early stage colorectal carcinoma metastasis.Scientific reports · 2021Article
- MONET: Multi-omic module discovery by omic selection.PLoS computational biology · 2020Article
- Inaccuracy of the log-rank approximation in cancer data analysis.Molecular systems biology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The log-rank test statistic is very broadly used in biology. Unfortunately, P-values based on the popular chi-square approximation are often inaccurate and can be misleading.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.