Evidence map›Paper›PMID 31464215›Full record

ReviewLung India : official organ of Indian Chest Society

Pidotimod: In-depth review of current evidence.

Ashok Mahashur, P K Thomas, Parthiv Mehta, Kundan Nivangune, Snehal Muchhala, Rishi Jain

Open access · diamondAbstract readReview
In one paragraph

Review in Lung India : official organ of Indian Chest Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. From Legacy to Innovation: Pidotimod's Expanding Therapeutic Horizon.Mediterranean journal of hematology and infectious diseases · 2025
    Review
  4. Pidotimod in pediatrics: new evidence and future perspectives.Multidisciplinary respiratory medicine · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Enantioselective Michael-Proton Transfer-Lactamization for Pyroglutamic Acid Derivatives: Synthesis of Dimethyl-(Organic syntheses; an annual publication of satisfactory methods for the preparation of organic chemicals · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Ashok MahashurPD Hinduja National Hospital and Medical Research Centre, Mumbai, Maharashtra, India.
P K ThomasDepartment of Respiratory Medicine, Apollo Clinic, Chennai, Tamil Nadu, India.
Parthiv MehtaDepartment of Respiratory Medicine, Mehta Hospital, Ahmedabad, Gujarat, India.
Kundan NivanguneDepartment of Medical Affairs, Wockhardt Limited, Mumbai, Maharashtra, India.
Snehal MuchhalaDepartment of Medical Affairs, Wockhardt Limited, Mumbai, Maharashtra, India.
Rishi JainDepartment of Medical Affairs, Wockhardt Limited, Mumbai, Maharashtra, India.
Wockhardt Hospitals · INAhmedabad Civil Hospital · INApollo Hospitals · INP. D. Hinduja Hospital and Medical Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pidotimod, an immunostimulant, is researched for over two decades. Current evidence indicates its utility in a variety of indications in children as well as in adults. Its immunostimulant activity has been firmly established in the management of recurrent respiratory infections in children with or without asthma. Compared to standard of care alone, addition of pidotimod to standard of care significantly prevents the recurrences and reduces the severity and duration of acute episodes, ultimately resulting in reduced visits to pediatric clinics and lower absenteeism at school. In adults, pidotimod is effective in the prevention and treatment of acute infectious exacerbations of chronic bronchitis and chronic obstructive pulmonary disease (COPD). Further, it has been evaluated in indications such as pneumonia, hand-food-mouth disease, bronchiectasis, and chronic idiopathic urticaria. From a total of 32 studies conducted in child (24 studies) and adult (8 studies) population, this in-depth review discusses the current evidence of pidotimod. With further exploration, the immunostimulant activity of pidotimod might be extended to different immunological disorders.

Indexed as

Adultsasthmachildrenchronic obstructive pulmonary diseasepidotimodrecurrent respiratory infections

Identifiers

PMID31464215
PMCPMC6710962
OpenAlexW2969843906

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.