Evidence map›Paper›PMID 31464204›Full record

ArticleAsian journal of andrology

Effect of probucol on autophagy and apoptosis in the penile tissue of streptozotocin-induced diabetic rats.

Ke-Qin Zhang, Tao Tian, Liang-Liang Hu, Hao-Ran Wang, Qiang Fu

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ke-Qin ZhangDepartment of Urology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, China.
Tao TianDepartment of Urology, Shandong Zaozhuang Municipal Hospital, Zaozhuang 277000, China.
Liang-Liang HuDepartment of Urology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, China.
Hao-Ran WangDepartment of Urology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, China.
Qiang FuDepartment of Urology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, China.
Shandong Provincial Hospital · CNShandong University · CNZaozhuang Municipal Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy and apoptosis have been regarded as important processes in the development of diabetic erectile dysfunction (DMED). Probucol is considered to have anti-apoptotic effects, but its relationship with autophagy has not been reported. The aim of this study was to investigate the effects and mechanisms of probucol on erectile function. Thirty Sprague-Dawley (SD) male rats (12 weeks old) were fasted for 12 h. Twenty SD rats were injected with a single intraperitoneal injection of 60 mg kg

Indexed as

AnimalsAntioxidantsApoptosisAutophagybcl-2-Associated X ProteinCaspase 3Diabetes Mellitus, ExperimentalErectile DysfunctionMaleMicrotubule-Associated ProteinsPenile ErectionPenisProbucolProto-Oncogene Proteins c-bcl-2RatsSequestosome-1 ProteinAntioxidantsAnxa3 protein, ratBax protein, ratbcl-2-Associated X ProteinBcl2 protein, ratCasp3 protein, ratCaspase 3Microtubule-Associated ProteinsmTOR protein, ratProbucolProto-Oncogene Proteins c-bcl-2Sequestosome-1 ProteinSqstm1 protein, ratTOR Serine-Threonine Kinasesapoptosisautophagyerectile dysfunctionprobucol

Identifiers

PMID31464204
PMCPMC7406090
OpenAlexW2969414626

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.