Evidence map›Paper›PMID 31464192›Full record

Trial reportJournal of medical Internet research2019

Comparison of the Effects of Coaching and Receipt of App Recommendations on Depression, Anxiety, and Engagement in the IntelliCare Platform: Factorial Randomized Controlled Trial.

David C Mohr, Stephen M Schueller, Kathryn Noth Tomasino, Susan M Kaiser, Nameyeh Alam, Chris Karr, Jessica L Vergara, Elizabeth L Gray, Mary J Kwasny, Emily G Lattie

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of medical Internet research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 67 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 5 pooled it
9.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02801877 nacompletednot on this map

Artificial Intelligence in a Mobile (AIM) Intervention for Depression

TypeinterventionalSponsorNorthwestern UniversityRan2016 to 2018Enrolled301ConditionsDepression, AnxietyArmsIntelliCare, Hub App with the Recommender System, Coaching
NCT05746767 naenrolling by invitationnot on this mapstarted 2024, after this paper: background citation

SUPERA: Supporting Peer Interactions to Expand Access to Digital Cognitive Behavioral Therapy for Spanish-speaking Safety-Net Patients in Primary Care

TypeinterventionalSponsorUniversity of California, IrvineRan2024 to 2028Enrolled426ConditionsDepression, AnxietyArmsSupported dCBT, Unsupported dCBT
3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 5 syntheses or guidelines pooled it, 128 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

David C MohrCenter for Behavioral Intervention Technologies, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-5443-7596
Stephen M SchuellerDepartment of Psychological Science, University of California, Irvine, Irvine, CA, United States.ORCID 0000-0002-1003-0399
Kathryn Noth TomasinoDepartment of Gastroenterology, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-4905-8807
Susan M KaiserCenter for Behavioral Intervention Technologies, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-5749-2072
Nameyeh AlamCenter for Behavioral Intervention Technologies, Northwestern University, Chicago, IL, United States.ORCID 0000-0001-5179-5972
Chris KarrAudacious Software, Chicago, IL, United States.ORCID 0000-0003-1828-4497
Jessica L VergaraCenter for Behavioral Intervention Technologies, Northwestern University, Chicago, IL, United States.ORCID 0000-0003-2644-1456
Elizabeth L GrayDepartment of Preventive Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0001-9298-6927
Mary J KwasnyDepartment of Preventive Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0003-3287-1903
Emily G LattieCenter for Behavioral Intervention Technologies, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-3069-5996
Northwestern University · USUniversity of California, Irvine · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Technology Enabled Services for Coordinated Care of Depression in Healthcare SettingsP50MH119029 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DAVID CURTIS MOHR, Jessica Lee Schleider · 2020 to 2026
$10.7M
Artificial Intelligence in a Mobile Intervention for Depression (AIM)R01MH100482 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MOHR, DAVID CURTIS · 2013 to 2017
$3.1M
Expanding College Student Mental Health with Stress Management Mobile TechnologiesK08MH112878 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LATTIE, EMILY GARDINER · 2017 to 2021
$746k
NCATS NIH HHS UL1 TR001422NIMH NIH HHS K08 MH112878NIMH NIH HHS P50 MH119029NIMH NIH HHS R01 MH100482
6 · The paper itself

Abstract

backgroundIntelliCare is a modular platform that includes 12 simple apps targeting specific psychological strategies for common mental health problems.

objectiveThis study aimed to examine the effect of 2 methods of maintaining engagement with the IntelliCare platform, coaching, and receipt of weekly recommendations to try different apps on depression, anxiety, and app use.

methodsA total of 301 participants with depression or anxiety were randomized to 1 of 4 treatments lasting 8 weeks and were followed for 6 months posttreatment. The trial used a 2X2 factorial design (coached vs self-guided treatment and weekly app recommendations vs no recommendations) to compare engagement metrics.

resultsThe median time to last use of any app during treatment was 56 days (interquartile range 54-57), with 253 participants (84.0%, 253/301) continuing to use the apps over a median of 92 days posttreatment. Receipt of weekly recommendations resulted in a significantly higher number of app use sessions during treatment (overall median=216; P=.04) but only marginal effects for time to last use (P=.06) and number of app downloads (P=.08). Coaching resulted in significantly more app downloads (P<.001), but there were no significant effects for time to last download or number of app sessions (P=.36) or time to last download (P=.08). Participants showed significant reductions in the Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7) across all treatment arms (P s<.001). Coached treatment led to larger GAD-7 reductions than those observed for self-guided treatment (P=.03), but the effects for the PHQ-9 did not reach significance (P=.06). Significant interaction was observed between receiving recommendations and time for the PHQ-9 (P=.04), but there were no significant effects for GAD-7 (P=.58).

conclusionsIntelliCare produced strong engagement with apps across all treatment arms. Coaching was associated with stronger anxiety outcomes, and receipt of recommendations enhanced depression outcomes.

trial registrationClinicalTrials.gov NCT02801877; https://clinicaltrials.gov/ct2/show/NCT02801877.

Indexed as

Anxiety DisordersDepressive DisorderFemaleHumansMaleMentoringMobile ApplicationsResearch Designanxietyclinical trialdepressionmHealth

Identifiers

PMID31464192
PMCPMC6737883
OpenAlexW2963665532

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.