ArticleBritish journal of pharmacology1988
Properties of intracellular calcium stores in pregnant rat myometrium.
Article in British journal of pharmacology, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 36 citations in OpenAlex.
- Myostimulating effect of sesamum radiatum aqueous leaf extract in isolated Guinea-pig Taenia caeci contractile activity.African journal of traditional, complementary, and alternative medicines : AJTCAM · 2011Article
- Contribution of sarcoplasmic reticular calcium to smooth muscle contractile activation: gestational dependence in isolated rat uterus.The Journal of physiology · 1998Article
- Differential expression of ryanodine receptor RyR2 mRNA in the non-pregnant and pregnant human myometrium.The Biochemical journal · 1997Article
- Intra-and intercellular calcium waves in cultured human myometrium.Journal of muscle research and cell motility · 1996Article
- Major difference between rat and guinea-pig ureter in the ability of agonists and caffeine to release Ca2+ and influence force.The Journal of physiology · 1995Article
- Prostaglandins and muscarinic agonists induce cyclic AMP attenuation by two distinct mechanisms in the pregnant-rat myometrium. Interaction between cyclic AMP and Ca2+ signals.The Biochemical journal · 1990Article
- Caffeine acting on pregnant rat myometrium: analysis of its relaxant action and its failure to release Ca2+ from intracellular stores.British journal of pharmacology · 1990Article
- AlF-4 inhibits the accumulation of Ca in the endoplasmic reticulum in intact myometrial strips, but not in the rabbit ear artery.Pflugers Archiv : European journal of physiology · 1989Article
- Ketamine-induced relaxation in intact and skinned smooth muscles of the rabbit ear artery.British journal of pharmacology · 1989Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
1. The properties of the Ca2+ stores in myometrium of 21-day pregnant rats were studied by recording the contractile responses of saponin-treated skinned muscles. 2. After accumulation of Ca2+ into the stores in the presence of 5 mM NaN3, inositol 1,4,5-trisphosphate (InsP3) at concentrations exceeding 3 microM produced a contraction. The amplitude of this contraction was maximal at about 20 microM. A second application of 20 microM InsP3 produced a smaller contraction than the first one. However after reloading the stores with Ca2+, 20 microM InsP3 produced a contraction of the same amplitude as the initial one. 3. After application of 20 microM InsP3, 1 microM A23187 still evoked a large contraction. If A23187 was applied first, the subsequent application of InsP3 or A23187 no longer induced a contraction, even after Ca2+ loading. 4. Guanosine triphosphate (GTP) or arachidonic acid, both 100 microM neither evoked a contraction nor enhanced the subsequent contraction elicited by 20 microM InsP3. 5. Caffeine 25 mM did not induce a contraction nor did it affect the contraction elicited by 20 microM InsP3. 6. The results indicate that in pregnant rat myometrium InsP3 releases Ca2+ from intracellular stores as has been proposed in vascular smooth muscles.
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