Evidence map›Paper›PMID 31463649›Full record

ArticleGeroScience2019

Validation of a digitally delivered visual paired comparison task: reliability and convergent validity with established cognitive tests.

Joshua L Gills, Jordan M Glenn, Erica N Madero, Nick T Bott, Michelle Gray

Abstract readValidation Study
In one paragraph

Article in GeroScience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  19. Unsupervised mobile cognitive testing for use in preclinical Alzheimer's disease.Alzheimer's & dementia (Amsterdam, Netherlands) · 2021
    Article
  20. An associative analysis of recognition memory: Relative recency effects in an eye-tracking paradigm.Journal of experimental psychology. Animal learning and cognition · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joshua L GillsExercise Science Research Center, University of Arkansas, Fayetteville, AR, USA.
Jordan M GlennVP Clinical Development, Neurotrack Technologies, Inc., University of Arkansas, Redwood City, CA, USA.
Erica N MaderoNeurotrack Technologies, Inc., Redwood City, CA, USA.
Nick T BottNeurotrack Technologies, Inc., Redwood City, CA, USA.
Michelle GrayExercise Science Research Center, University of Arkansas, Fayetteville, AR, USA. rgray@uark.edu.ORCID 0000-0001-5721-9087

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) affects the memory and cognitive function of approximately 5.7 million Americans. Early detection subsequently allows for earlier treatment and improves outcomes. Currently, there exists a validated 30-min eye-tracking cognitive assessment (VPC-30) for predicting AD risk. However, a shorter assessment would improve user experience and improve scalability. Thus, the purposes were to (1) determine convergent validity between the 5-min web camera-based eye-tracking task (VPC-5) and VPC-30, (2) examine the relationship between VPC-5 and gold-standard cognitive tests, and (3) determine the reliability and stability of VPC-5. This prospective study included two healthy cohorts: older adults (65+ years, n = 20) and younger adults (18-46 years, n = 24). Participants were tested on two separate occasions. Visit 1 included the Montreal Cognitive Assessment (MoCA), Digit Symbol Coding test (DSC), NIH Toolbox Cognitive Battery (NIHTB-CB), VPC-30, and VPC-5. Visit 2 occurred at least 14 days later; participants completed the VPC-5, DSC, NIHTB-CB, and dual-task walking assessments (DT). VPC-30 significantly correlated with VPC-5 at the first (p < .001) and second (p = .001) time points. VPC-5 and DSC (p < .01) and Pattern Comparison Processing Speed Test (PSPAC) (p = .01) were also correlated on day 1. Significant associations existed between VPC-5 and DSC (p < .001), Flanker Inhibitory Control Test (p = .05), PSPAC (p < .001), and Picture Sequence Memory Test (p = .02) during day 14 testing session. The test retest reliability of VPC-5 was significant (p < .001). VPC-5 displayed moderate convergent validity with the VPC-30 and gold-standard measures of cognition, while demonstrating strong stability, suggesting it is a valuable assessment for monitoring memory function.

Indexed as

Eye MovementsNeuropsychological TestsAdolescentAdultAgedAged, 80 and overAlzheimer DiseaseFemaleHumansMaleMiddle AgedProspective StudiesReproducibility of ResultsWalking SpeedYoung AdultAlzheimer’s diseaseCognitionDementiaVisual paired comparison

Identifiers

PMID31463649
PMCPMC6815320

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.