Evidence map›Paper›PMID 31463557›Full record

ArticleOral and maxillofacial surgery2019

Safety of resection margins in CAD/CAM-guided primarily reconstructed oral squamous cell carcinoma-a retrospective case series.

Elisabeth Goetze, Maximillian Moergel, Matthias Gielisch, Peer W Kämmerer

Abstract read
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In one paragraph

Article in Oral and maxillofacial surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. [Treatment of tuberculosis in craniovertebral junction].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2020
    Article
  8. [An application of posterior cervical and transoral approaches to treating primary malignant osseous tumors in craniovertebral junction].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2020
    Article
  9. [Digitalization and use of artificial intelligence in microvascular reconstructive facial surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elisabeth GoetzeDepartment of Oral, Maxillofacial and Plastic Surgery, University Medical Centre Mainz, Augustusplatz 2, 55131, Mainz, Germany.
Maximillian MoergelDepartment of Oral, Maxillofacial and Plastic Surgery, University Medical Centre Mainz, Augustusplatz 2, 55131, Mainz, Germany.
Matthias GielischDepartment of Oral, Maxillofacial and Plastic Surgery, University Medical Centre Mainz, Augustusplatz 2, 55131, Mainz, Germany.
Peer W KämmererDepartment of Oral, Maxillofacial and Plastic Surgery, University Medical Centre Mainz, Augustusplatz 2, 55131, Mainz, Germany. peer.kaemmerer@gmx.de.ORCID http://orcid.org/0000-0002-1671-3764

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAfter resection of malignancies of the jaws, CAD/CAM procedures have become standard for primary bony reconstruction. Even so, these techniques may limit surgical resection safety. Therefore, the aim of the study was to examine osseous as well as soft tissue resection margins after CAD/CAM-guided tumor resections and reconstructions.

methodsA retrospective analysis of patients treated with oral squamous cell carcinoma (OSCC) from 2014 to 2019 was performed. Inclusion criteria were CAD/CAM-guided osseous resection and primary reconstruction. Evaluation was performed for histological confirmed resection margins (hard and soft tissue) as well as recurrence of the disease related to the resection status.

resultsIn 46 patients, bony resection margins were classified: tumor free (R0 41/46), microscopical invasion (R1 1/46), and close margin (R0 < 4 mm 4/46) respectively for soft tissue 29/46 tumor free (R0), 7/46 close margin (R0 < 4 mm), 5/46 R1, and 4/46 could not be further determined (Rx). Fourteen patients (14/46) showed recurrent disease (2/46 locoregional) without association with the bony resection margin status. Recurrence occurred predominantly (13/46) in high-staged tumor patients. R1/close margin/Rx resection of the soft tissue resulted in a significant earlier recurrence when compared with R0 resection.

conclusionCAD/CAM procedure allows safe tumor resection with the profit of a guided and accurate reconstruction. In contrast to positive soft tissue margins, positive bony resection margins did not increase recurrence parameters.

Indexed as

Carcinoma, Squamous CellMouth NeoplasmsHumansMargins of ExcisionNeoplasm Recurrence, LocalPrognosisRetrospective StudiesCAD/CAM guidedCutting guidesMicrovascular reconstructionPrimary reconstructionResection margins

Identifiers

PMID31463557

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.