Evidence map›Paper›PMID 31463422›Full record

SynthesisBJS open2019

Meta-analysis of the association of extraintestinal manifestations with the development of pouchitis in patients with ulcerative colitis.

K Hata, S Okada, T Shinagawa, T Toshiaki, K Kawai, H Nozawa

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BJS open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Onset of pouchitis after colectomy for ulcerative colitis: reducing the risk.Expert review of gastroenterology & hepatology · 2025
    Article
  5. Article
  6. Review
  7. Pouchitis: pathophysiology and management.Nature reviews. Gastroenterology & hepatology · 2024
    Review
  8. Article
  9. The aetiology of pouchitis in patients with inflammatory bowel disease.Therapeutic advances in gastroenterology · 2024
    Review
  10. Article
  11. Article
  12. Increasing Incidence of Pouchitis Between 1996 and 2018: A Population-Based Danish Cohort Study.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023
    Article
  13. Pouchitis: insight into the pathogenesis and clinical aspects.American journal of translational research · 2022
    Review
  14. Article
  15. Clinical Discrimination of Chronic Pouchitis After Ileal Pouch-Anal Anastomosis in Patients with Ulcerative Colitis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
  16. Article
  17. Pouchitis: Treatment dilemmas at different stages of the disease.United European gastroenterology journal · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

K HataDepartment of Surgical Oncology The University of Tokyo 7-3-1 Hongo, Bunkyo-ku Tokyo, 113-8655 Japan.ORCID 0000-0003-4064-8701
S OkadaDepartment of Surgical Oncology The University of Tokyo 7-3-1 Hongo, Bunkyo-ku Tokyo, 113-8655 Japan.
T ShinagawaDepartment of Surgical Oncology The University of Tokyo 7-3-1 Hongo, Bunkyo-ku Tokyo, 113-8655 Japan.
T ToshiakiDepartment of Surgical Oncology The University of Tokyo 7-3-1 Hongo, Bunkyo-ku Tokyo, 113-8655 Japan.ORCID 0000-0001-8880-0042
K KawaiDepartment of Surgical Oncology The University of Tokyo 7-3-1 Hongo, Bunkyo-ku Tokyo, 113-8655 Japan.
H NozawaDepartment of Surgical Oncology The University of Tokyo 7-3-1 Hongo, Bunkyo-ku Tokyo, 113-8655 Japan.ORCID 0000-0002-7891-5986
University of Tokyo Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The presence of extraintestinal manifestations may be associated with the development of pouchitis in patients with ulcerative colitis after ileal pouch-anal anastomosis. The aim of this study was to assess this correlation. Methods: A systematic literature search was performed using MEDLINE and the Cochrane Library. Studies published in English up to 22 May 2017 investigating the association between extraintestinal manifestations and development of pouchitis in adults with ulcerative colitis were included. Case reports were excluded. The association of extraintestinal manifestations with the development of overall and chronic pouchitis was investigated using a random-effects model. Results: Of 1010 citations identified, 22 observational studies comprising 5128 patients were selected for analysis. The presence of extraintestinal manifestations was significantly associated with both chronic pouchitis (odds ratio 2·28, 95 per cent c.i. 1·57 to 3·32; Conclusion: The presence of extraintestinal manifestations is associated with development of pouchitis after ileal pouch-anal anastomosis.

Indexed as

Postoperative ComplicationsPouchitisProctocolectomy, RestorativeCholangitis, SclerosingColitis, UlcerativeHumansRisk Factors

Identifiers

PMID31463422
PMCPMC6706792
OpenAlexW2921909223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.