ArticleJournal of thoracic disease2019
Visceral pleural invasion in T1 tumors (≤3 cm), particularly T1a, in the eighth tumor-node-metastasis classification system for non-small cell lung cancer: a population-based study.
Article in Journal of thoracic disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Prognostic Impact of Visceral Pleural Invasion in Node-Negative Non-Small Cell Lung Cancer with Tumors ≤ 3 cm.Cancers · 2026Article
- CT predictors of visceral pleural invasion in subsolid nodular pulmonary adenocarcinoma: differences between direct and indirect tumor-pleura contact.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Observational
- Contrast-enhanced CT-based radiomics for predicting visceral pleural invasion in early-stage non-small cell lung cancer.Insights into imaging · 2026Article
- Characterization of pleural metastasis in non-small cell carcinomas undergoing intraoperative frozen section examination.Journal of thoracic disease · 2025Article
- Integrating radiomics features and CT semantic characteristics for predicting visceral pleural invasion in clinical stage Ia peripheral lung adenocarcinoma.Discover oncology · 2025Article
- Prediction of visceral pleural invasion of clinical stage IA lung adenocarcinoma based on computed tomography features.Translational cancer research · 2025Article
- Nomogram using intratumoral and peritumoral radiomics for the preoperative prediction of visceral pleural invasion in clinical stage IA lung adenocarcinoma.Journal of cardiothoracic surgery · 2024Article
- Research progress in predicting visceral pleural invasion of lung cancer: a narrative review.Translational cancer research · 2024Review
- Using the length of pleural tag to predetermine pleural invasion by lung adenocarcinomas.Frontiers in oncology · 2024Article
- Predictive value of SUVmax in visceral pleural invasive lung adenocarcinoma with different diameters.Nuclear medicine communications · 2023Article
- Development and validation ofAnnals of nuclear medicine · 2023Article
- Article
- Multivariate analysis based on the maximum standard unit value ofDiagnostic and interventional radiology (Ankara, Turkey) · 2023Article
- Establishment and Validation of a Predictive Nomogram for Postoperative Survival of Stage I Non-Small Cell Lung Cancer.International journal of general medicine · 2022Article
- Rethinking the Selection of Pathological T-Classification for Non-Small-Cell Lung Cancer in Varying Degrees of Visceral Pleural Invasion: A SEER-Based Study.Frontiers in surgery · 2022Article
- Risk analysis in peripheral clinical T1 non-small cell lung cancer correlations between tumor-to-blood standardized uptake ratio onQuantitative imaging in medicine and surgery · 2022Article
- The combination of computed tomography features and circulating tumor cells increases the surgical prediction of visceral pleural invasion in clinical T1N0M0 lung adenocarcinoma.Translational lung cancer research · 2021Article
- A predictive model for identifying candidates for adjuvant chemotherapy based on recurrence risk profile of resected, node-negative (N0) non-small cell lung cancer.Journal of thoracic disease · 2021Article
- Identifying optimal candidates for primary tumor resection among metastatic non-small cell lung cancer patients: a population-based predictive model.Translational lung cancer research · 2021Article
- The Study of Tumor Volume as a Prognostic Factor in T Staging System for Non-Small Cell Lung Cancer: An Exploratory Study.Technology in cancer research & treatmentArticle
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Abstract
backgroundWe aimed to validate the tumor (T) descriptors of visceral pleural invasion (VPI) for T1 tumors (<3 cm) in the 8th edition of the tumor-node-metastasis (TNM) classification system and the prognostic value of VPI for resected T1a tumors.
methodsThe external cohort consisted of 23,501 patients with resected pN0 non-small cell lung cancer (NSCLC) selected from the Surveillance, Epidemiology, and End Results (SEER) database (2010 to 2013). The classification of T1 tumors with VPI was investigated using survival curves. The internal cohort consisted of patients diagnosed with pN0 NSCLC between 2011 and 2013 at Guangdong Lung Cancer Institute. The prognostic value of VPI for T1a tumors (<1 cm) was further assessed in these two cohorts.
resultsThe overall survival (OS) and lung cancer-specific survival (LCSS) of the T1-VPI group and groups of each T stage (size only) were compared in the external (SEER) cohort. There were no significant survival differences between the T1-VPI and T2a groups (OS: P=0.706; LCSS: P=0.792) and T1-VPI and T2b groups, although the latter showed a trend toward lower P-values (OS: P=0.117; LCSS: P=0.094). In the internal cohort, a significant difference in OS was observed between patients with T1-VPI and those with T2b (P=0.049). Among patients with T1a tumors and VPI in the SEER database, the prognosis of the non-sub-lobectomy group was superior to that of the sub-lobectomy group, with intrathoracic recurrence as the predominant relapse pattern of T1 tumors with VPI (69.2%).
conclusionsT1 tumors (<3 cm) with VPI can be staged as T2a in the 8th TNM staging system and surgical resection of T1a tumors is a concern when VPI is present.
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