Evidence map›Paper›PMID 31463070›Full record

ArticleTropical diseases, travel medicine and vaccines2019

Imported visceral leishmaniasis and immunosuppression in seven Norwegian patients.

Thomas Schwartz, Mogens Jensenius, Bjørn Blomberg, Cathrine Fladeby, Arild Mæland, Frank O Pettersen

Open access · goldAbstract read
In one paragraph

Article in Tropical diseases, travel medicine and vaccines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Thomas Schwartz1Department of Infectious Diseases, Ullevål, Oslo University Hospital, Oslo, Norway.
Mogens Jensenius1Department of Infectious Diseases, Ullevål, Oslo University Hospital, Oslo, Norway.
Bjørn Blomberg3Norwegian National Advisory Unit on Tropical Infectious Diseases. Department of Medicine, Haukeland University Hospital, Bergen, Norway.
Cathrine Fladeby5Department of Microbiology, Ullevål, Oslo University Hospital, Oslo, Norway.
Arild Mæland1Department of Infectious Diseases, Ullevål, Oslo University Hospital, Oslo, Norway.
Frank O Pettersen1Department of Infectious Diseases, Ullevål, Oslo University Hospital, Oslo, Norway.
Oslo University Hospital · NOUniversity of Bergen · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVisceral leishmaniasis (VL) is a protozoal disease that may be aggravated by immunosuppression. In recent years, a growing number of patients with chronic diseases use biological treatment. When such immunosuppressed patients travel to endemic areas, they are facing the risk of VL. Increased incidence of leishmaniasis is reported in endemic areas like the Mediterranean basin, an area frequently visited by Norwegian tourists. This may lead to an increased number of patients, many presenting to health personnel unfamiliar with the disease, in their home countries.

methodsWe reviewed the files of seven immunosuppressed patients with VL, admitted to Oslo and Haukeland University Hospitals in Norway in the period 2009-2018.

resultsThe patients were 41-83 (median 66) years of age; four had rheumatic disease all of whom used methotrexate; one had advanced HIV infection, one had inflammatory bowel disease and one had myelofibrosis.

conclusionsVisceral leishmaniasis is a potentially life-threatening but usually treatable condition. It is endemic in Southern Europe, including popular tourist destinations such as the Mediterranean basin. It is relatively unknown to most medical practitioners in non-endemic areas and clinical vigilance is required to identify those who are infected.

Indexed as

Autoimmune diseaseImmunosuppressionLeishmaniasisMethotrexateRheumatic diseaseTravel medicineTumor necrosis factor alpha inhibitor

Identifiers

PMID31463070
PMCPMC6704524
OpenAlexW2969560299

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.